Bliemel Christopher, Buecking Benjamin, Oberkircher Ludwig, Knobe Matthias, Ruchholtz Steffen, Eschbach Daphne
Center for Orthopaedics and Trauma Surgery, University Hospital Marburg, Baldingerstrasse, 35043, Marburg, Germany.
Department of Orthopaedic Trauma, University of Aachen Medical Center, Aachen, Germany.
Int Orthop. 2017 Oct;41(10):1995-2000. doi: 10.1007/s00264-017-3591-2. Epub 2017 Aug 9.
Due to pre-existing illnesses, elderly hip fracture patients represent a vulnerable patient population. The present study was conducted to investigate the effects of various pre-existing conditions on the outcomes of hip fracture patients.
A total of 402 surgically treated geriatric hip fracture patients were included in this prospective, single-centre study. Upon admission, patient age, gender and fracture type were documented, among other information. Patients were divided into six groups according to their pre-existing illness (neurological, cardiovascular, respiratory, gastrointestinal, renal or musculoskeletal). Outcomes in all six patient groups were measured using the following outcome parameters: length of hospital stay, mobility, functional results and mortality rate at discharge and at the one-year follow-up examination.
Reduced values for the pre-fracture Barthel index (BI) were detected in patients with neurological (p < 0.001) and kidney-related diseases (p = 0.001). Neurological and kidney-related diseases were associated with reduced values on the BI (p < 0.001; p = 0.002) and Tinetti test (TT) (p < 0.001; p = 0.004) as well as an increased mortality rate (p < 0.001; p < 0.001) at the one-year follow-up. In addition, patients with respiratory (p = 0.004) and gastrointestinal disorders (p = 0.007) had an increased mortality rate in the medium term.
Pre-existing conditions are common among geriatric hip fracture patients. Pre-existing neurological and kidney-related diseases had the highest impact on functional outcomes and mortality rates at the end of acute care and in the medium term. In contrast to pre-existing cardiovascular disease, pre-existing neurological, kidney, respiratory and gastrointestinal disorders were also found to be associated with increased mortality rates in the medium term.
由于存在基础疾病,老年髋部骨折患者是一个脆弱的患者群体。本研究旨在调查各种基础疾病对髋部骨折患者治疗结果的影响。
本前瞻性单中心研究共纳入402例接受手术治疗的老年髋部骨折患者。入院时记录患者年龄、性别和骨折类型等信息。根据患者的基础疾病(神经、心血管、呼吸、胃肠道、肾脏或肌肉骨骼疾病)将患者分为六组。使用以下结局参数测量所有六组患者的结局:住院时间、活动能力、功能结果以及出院时和一年随访检查时的死亡率。
神经疾病(p < 0.001)和肾脏相关疾病(p = 0.001)患者的骨折前巴氏指数(BI)值降低。神经疾病和肾脏相关疾病与BI值降低(p < 0.001;p = 0.002)和Tinetti测试(TT)值降低(p < 0.001;p = 0.004)以及一年随访时死亡率增加(p < 0.001;p < 0.001)相关。此外,患有呼吸疾病(p = 0.004)和胃肠道疾病(p = 0.007)的患者中期死亡率增加。
基础疾病在老年髋部骨折患者中很常见。基础神经疾病和肾脏相关疾病对急性治疗末期和中期的功能结局和死亡率影响最大。与基础心血管疾病不同,基础神经、肾脏、呼吸和胃肠道疾病在中期也与死亡率增加相关。