Hibi Arata, Kasugai Takahisa, Kamiya Keisuke, Kamiya Keisuke, Ito Chiharu, Kominato Satoru, Mizuguchi Ken, Miura Toshiyuki, Koyama Katsushi
Division of Nephrology and Rheumatology, Department of Internal Medicine, Kariya Toyota General Hospital, 5-15, Sumiyoshi-cho, Kariya, Aichi, 448-8505, Japan.
Division of Nephrology and Rheumatology, Department of Internal Medicine, Aichi Medical University Hospital, 1-1 Yazakokarimata, Nagakute, Aichi, 480-1195, Japan.
CEN Case Rep. 2017 Nov;6(2):175-179. doi: 10.1007/s13730-017-0270-5. Epub 2017 Aug 9.
An 89-year-old Japanese man on peritoneal dialysis (PD) was suspected of having a PD-associated catheter infection. He visited the hospital because of the discharge of pus from the exit site of his catheter. Gram staining of the pus showed Gram-positive bacilli, but these were acid-fast bacilli. The rapidly growing nontuberculous mycobacteria, Mycobacterium abscessus, was isolated. PD catheter removal and debridement were immediately performed. The patient received combination antibiotic therapy. His clinical course was good, but he required hemodialysis due to the discontinuation of PD. However, the patient and his family chose not to continue hemodialysis even when the symptoms of uremia appeared. Best supportive care was arranged by his primary care physician. M. abscessus is a rare causative organism for PD-associated catheter infections and is difficult to treat. In our case, a rapid and precise diagnosis was made using acid-fast staining and Mycobacterium culture. The risk of nontuberculous mycobacterial infections should be considered in patients on PD.
一名接受腹膜透析(PD)的89岁日本男性被怀疑发生了与PD相关的导管感染。他因导管出口处有脓液排出而前来就诊。脓液的革兰氏染色显示为革兰氏阳性杆菌,但这些杆菌为抗酸杆菌。分离出了快速生长的非结核分枝杆菌——脓肿分枝杆菌。立即进行了PD导管拔除和清创术。患者接受了联合抗生素治疗。他的临床病程良好,但由于停止了PD治疗,他需要进行血液透析。然而,即使出现了尿毒症症状,患者及其家属仍选择不继续进行血液透析。其初级保健医生安排了最佳支持治疗。脓肿分枝杆菌是与PD相关导管感染的一种罕见病原体,且难以治疗。在我们的病例中,通过抗酸染色和分枝杆菌培养进行了快速而准确的诊断。对于接受PD治疗的患者,应考虑非结核分枝杆菌感染的风险。