2009 - 2017年丹麦从人类感染病例中分离出的沙门氏菌中携带质粒的黏菌素耐药基因mcr - 3
Plasmid-borne colistin resistance gene mcr-3 in Salmonella isolates from human infections, Denmark, 2009-17.
作者信息
Litrup Eva, Kiil Kristoffer, Hammerum Anette M, Roer Louise, Nielsen Eva M, Torpdahl Mia
机构信息
Department of Bacteria, Parasites and Fungi, Statens Serum Institut, Copenhagen, Denmark.
出版信息
Euro Surveill. 2017 Aug 3;22(31). doi: 10.2807/1560-7917.ES.2017.22.31.30587.
This report describes one Salmonella isolate harbouring both mcr-1 and mcr-3. We also found nine other Salmonella isolates positive for the plasmid-borne colistin resistance gene, mcr-3. The strains were isolated from patients in Denmark between 2009 and 2017 and five of the patients had travelled to Asia. In addition to mcr-3, all strains were found positive for bla, strA, strB, sul2 and tet(A) or tet(B), and most strains were positive for bla and qnrS.
本报告描述了一株同时携带mcr-1和mcr-3的沙门氏菌分离株。我们还发现另外9株沙门氏菌分离株携带质粒介导的粘菌素耐药基因mcr-3呈阳性。这些菌株于2009年至2017年间从丹麦的患者中分离得到，其中5名患者曾前往亚洲。除mcr-3外，所有菌株的bla、strA、strB、sul2和tet(A)或tet(B)检测均呈阳性，且大多数菌株的bla和qnrS检测也呈阳性。
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