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Effect of antihypertensive treatment at different blood pressure levels in patients with diabetes mellitus: systematic review and meta-analyses.糖尿病患者不同血压水平下降压治疗的效果:系统评价与荟萃分析
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糖尿病患者心血管疾病的一级预防

Primary Prevention of Cardiovascular Disease in Diabetes Mellitus.

作者信息

Newman Jonathan D, Schwartzbard Arthur Z, Weintraub Howard S, Goldberg Ira J, Berger Jeffrey S

机构信息

Division of Cardiology and the Center for the Prevention of Cardiovascular Disease, Department of Medicine, New York University Medical Center; New York, New York.

Division of Cardiology and the Center for the Prevention of Cardiovascular Disease, Department of Medicine, New York University Medical Center; New York, New York.

出版信息

J Am Coll Cardiol. 2017 Aug 15;70(7):883-893. doi: 10.1016/j.jacc.2017.07.001.

DOI:10.1016/j.jacc.2017.07.001
PMID:28797359
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5656394/
Abstract

Type 2 diabetes mellitus (T2D) is a major risk factor for cardiovascular disease (CVD), the most common cause of death in T2D. Yet, <50% of U.S. adults with T2D meet recommended guidelines for CVD prevention. The burden of T2D is increasing: by 2050, approximately 1 in 3 U.S. individuals may have T2D, and patients with T2D will comprise an increasingly large proportion of the CVD population. The authors believe it is imperative that we expand the use of therapies proven to reduce CVD risk in patients with T2D. The authors summarize evidence and guidelines for lifestyle (exercise, nutrition, and weight management) and CVD risk factor (blood pressure, cholesterol and blood lipids, glycemic control, and the use of aspirin) management for the prevention of CVD among patients with T2D. The authors believe appropriate lifestyle and CVD risk factor management has the potential to significantly reduce the burden of CVD among patients with T2D.

摘要

2型糖尿病(T2D)是心血管疾病(CVD)的主要危险因素,而心血管疾病是T2D最常见的死亡原因。然而,在美国患有T2D的成年人中,只有不到50%符合推荐的CVD预防指南。T2D的负担正在增加:到2050年,大约三分之一的美国人可能患有T2D,并且T2D患者在CVD人群中所占比例将越来越大。作者认为,我们必须扩大使用已被证明可降低T2D患者CVD风险的治疗方法。作者总结了生活方式(运动、营养和体重管理)以及CVD危险因素(血压、胆固醇和血脂、血糖控制以及阿司匹林的使用)管理的证据和指南,以预防T2D患者的CVD。作者认为,适当的生活方式和CVD危险因素管理有可能显著减轻T2D患者的CVD负担。