雌激素诱导未成熟大鼠子宫中癌基因的表达。
Oestrogen-induced expression of oncogenes in the immature rat uterus.
作者信息
Travers M T, Knowler J T
出版信息
FEBS Lett. 1987 Jan 19;211(1):27-30. doi: 10.1016/0014-5793(87)81267-x.
PMID:2879741
Abstract
4 h after a single precocious administration of oestrogen there was a considerable but short-lived surge in the uterine levels of myc-encoded polyadenylated mRNA. This was followed by a further peak 28 h after hormone administration. The expression of rasHa showed a totally different time course with a build up of hybridizable message that peaked 8 h after oestrogen administration.
摘要
单次过早给予雌激素4小时后，子宫中myc编码的多聚腺苷酸化mRNA水平出现显著但短暂的激增。激素给药28小时后出现进一步的峰值。rasHa的表达呈现出完全不同的时间进程，可杂交信息逐渐积累，在雌激素给药8小时后达到峰值。
Zotero 插件