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经腹腔镜行腹式环扎术预防早产的系统评价。

Systematic Review of Transabdominal Cerclage Placed via Laparoscopy for the Prevention of Preterm Birth.

机构信息

Departments of Minimally Invasive Gynecologic Surgery, George Washington University, Washington, DC.

Department of Obstetrics and Gynecology, George Washington University, Washington, DC.

出版信息

J Minim Invasive Gynecol. 2018 Feb;25(2):277-286. doi: 10.1016/j.jmig.2017.07.021. Epub 2017 Aug 7.

Abstract

Preterm birth is the leading cause of neonatal mortality and morbidity. Multiple interventions are available to minimize this occurrence; however, despite current recommendations including medical management, cervical length screening, and transvaginal cerclage, a substantial number of women still experience preterm birth. For those patients, experts recommend transabdominal cerclage (TAC). In this systematic review, we compared 26 studies (1116 patients) of TAC placed via laparotomy (TAC-lap) and 15 studies (728 patients) of TAC placed via laparoscopy (TAC-lsc). There was no significant difference in overall neonatal survival between the TAC-lsc and TAC-lap groups (89.9% vs 90.8%, respectively; p = .80). When T1 losses were excluded, the neonatal survival rate was significantly higher for the TAC-lsc group (96.5% vs 90.1%; p < .01). In terms of obstetrical outcomes, the TAC-lsc group had a higher rate of deliveries at gestational age (GA) > 34 weeks (82.9% vs 76%; p < .01) and a lower rate of deliveries at GA 23.0 to 33.6 weeks (6.8% vs 14.8%; p < .01). The TAC-lsc group also had fewer T2 losses (3.2% vs 7.8%; p < .01). TAC-lsc offers all the benefits of minimally invasive surgery with better obstetrical outcomes compared with TAC-lap.

摘要

早产是新生儿死亡和发病的主要原因。有多种干预措施可尽量减少这种情况的发生;然而,尽管目前的建议包括医学管理、宫颈长度筛查和经阴道宫颈环扎术,但仍有相当数量的女性发生早产。对于这些患者,专家建议进行经腹宫颈环扎术(TAC)。在这项系统评价中,我们比较了经剖腹手术(TAC-lap)和经腹腔镜(TAC-lsc)放置 TAC 的 26 项研究(1116 例患者)和 15 项研究(728 例患者)。TAC-lsc 组和 TAC-lap 组之间的总体新生儿存活率无显著差异(分别为 89.9%和 90.8%;p = .80)。当排除 T1 丢失时,TAC-lsc 组的新生儿存活率显著更高(96.5%比 90.1%;p < .01)。在产科结局方面,TAC-lsc 组的妊娠周数(GA)> 34 周的分娩率更高(82.9%比 76%;p < .01),GA 为 23.0 至 33.6 周的分娩率更低(6.8%比 14.8%;p < .01)。TAC-lsc 组的 T2 丢失率也较低(3.2%比 7.8%;p < .01)。与 TAC-lap 相比,TAC-lsc 具有微创外科手术的所有优势,且具有更好的产科结局。

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