Bilotta Claudio, Bergamaschini Luigi, Spreafico Sibilla, Vergani Carlo
Geriatric Medicine Unit, Department of Internal Medicine, Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, University of Milan, via Pace 9, 20122 Milan, Italy.
Eur J Ageing. 2010 Jan 28;7(1):29-35. doi: 10.1007/s10433-010-0138-4. eCollection 2010 Mar.
Late-life depression is associated with disabled functioning and a poor quality of life (QOL). The aim of this cross-sectional study was to find out whether the attendance of a day care centre (DC) was associated with QOL in community-dwelling older adults suffering from a depressive disorder without dementia. The study enrolled 149 depressed older adults aged 70 or older, who consecutively underwent a comprehensive geriatric assessment from April to July 2008 at the Geriatric Medicine Unit of the Fondazione Ospedale Maggiore Policlinico in Milan, Italy. QOL was evaluated by means of the European Quality of Life Visual Analogue Scale (EuroQol VAS). DC attendance was quantified as number of days of attendance per week in the past month. Participants attending a DC at least once a week ( = 17) had a higher mean EuroQol VAS score than non-attendants ( = 132) (mean ± SD 58.8 ± 19 vs. 45.3 ± 22.5; = 0.019). In multiple linear regression analysis a higher weekly attendance of DCs was related to a better quality of life according to the EuroQol VAS score (unstandardized coefficient 3.048, 95% CI 0.063-6.033, = 0.045) after correction for age, sex, balance and gait abilities, comorbidity, pharmacotherapy, living alone, and severity of depression. Therefore, in older outpatients suffering from a depressive disorder without dementia the attendance of a DC was an independent correlate of the QOL. A randomized controlled longitudinal study will be necessary to determine whether attending a DC is really effective on the QOL in the management of late-life depression.
老年期抑郁症与功能障碍及生活质量低下相关。本横断面研究的目的是了解日间护理中心（DC）的参与情况是否与社区居住的无痴呆症抑郁症老年患者的生活质量相关。该研究纳入了149名70岁及以上的抑郁症老年患者，他们于2008年4月至7月在意大利米兰马焦雷综合医院基金会老年医学科连续接受了全面的老年医学评估。生活质量通过欧洲生活质量视觉模拟量表（EuroQol VAS）进行评估。DC参与情况以过去一个月每周的参与天数来量化。每周至少参加一次DC的参与者（n = 17）的EuroQol VAS平均得分高于未参与者（n = 132）（均值±标准差 58.8±19 对 45.3±22.5；P = 0.019）。在多元线性回归分析中，在校正年龄、性别、平衡和步态能力、合并症、药物治疗、独居情况以及抑郁严重程度后，DC每周参与次数越多与根据EuroQol VAS评分得出的更好生活质量相关（非标准化系数3.048，95%置信区间0.063 - 6.033，P = 0.045）。因此，在无痴呆症的抑郁症老年门诊患者中，DC的参与是生活质量的一个独立相关因素。有必要进行一项随机对照纵向研究，以确定参加DC对老年期抑郁症管理中的生活质量是否真的有效。
