下颌骨浆细胞骨髓瘤的超微结构

Ultrastructure of a plasma-cell myeloma in the mandible.

作者信息

Chen S Y

出版信息

Oral Surg Oral Med Oral Pathol. 1979 Jul;48(1):57-63. doi: 10.1016/0030-4220(79)90237-8.

Abstract

Tumor cells exhibited large amounts of rough endoplasmic reticulum arranged in a lamellar pattern, large numbers of mitochondria with a perinuclear distribution, and a prominent Golgi complex, but only a small number of immunoglobulin granules. No crystalline structures of immunoglobulins were observed. Nuclei exhibited patchy condensation of chromatin and large nucleoli. The ultrastructural features suggest that this case could be a "resecretory" myeloma.

摘要

肿瘤细胞显示出大量呈板层状排列的粗面内质网、大量核周分布的线粒体以及一个显著的高尔基体复合体，但仅有少量免疫球蛋白颗粒。未观察到免疫球蛋白的晶体结构。细胞核表现出染色质的斑片状凝聚和大核仁。超微结构特征提示该病例可能为“再分泌型”骨髓瘤。