Defence Laboratory, Defence Research and Development Organization, Jodhpur, India.
Int Wound J. 2017 Dec;14(6):1276-1289. doi: 10.1111/iwj.12797. Epub 2017 Aug 10.
Chitin and chitosan are biopolymers with excellent bioactive properties, such as biodegradability, non-toxicity, biocompatibility, haemostatic activity and antimicrobial activity. A wide variety of biomedical applications for chitin and chitin derivatives have been reported, including wound-healing applications. They are reported to promote rapid dermal regeneration and accelerate wound healing. A number of dressing materials based on chitin and chitosan have been developed for the treatment of wounds. Chitin and chitosan with beneficial intrinsic properties and high potential for wound healing are attractive biopolymers for wound management. This review presents an overview of properties, biomedical applications and the role of these biopolymers in wound care.
壳聚糖和壳聚糖是具有优异生物活性的生物聚合物,如可生物降解性、无毒、生物相容性、止血活性和抗菌活性。已经报道了壳聚糖及其衍生物在各种生物医学中的应用,包括伤口愈合应用。据报道,它们能促进皮肤的快速再生并加速伤口愈合。已经开发了许多基于壳聚糖的敷料材料来治疗伤口。具有有益的固有特性和高伤口愈合潜力的壳聚糖和壳聚糖是用于伤口管理的有吸引力的生物聚合物。本综述介绍了这些生物聚合物的特性、生物医学应用以及它们在伤口护理中的作用。