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日本环境与儿童研究中母亲睡眠与小于胎龄儿:一项队列研究

Maternal sleep and small for gestational age infants in the Japan Environment and Children's Study: a cohort study.

作者信息

Morokuma Seiichi, Shimokawa Mototsugu, Kato Kiyoko, Sanefuji Masafumi, Shibata Eiji, Tsuji Mayumi, Senju Ayako, Kawamoto Toshihiro, Kusuhara Koichi

机构信息

Research Center for Environmental and Developmental Medical Sciences, Kyushu University, Fukuoka, Japan.

Department of Obstetrics and Gynecology, Kyushu University Hospital, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.

出版信息

BMC Res Notes. 2017 Aug 11;10(1):394. doi: 10.1186/s13104-017-2675-9.

Abstract

OBJECTIVES

Small for gestational age infants have an increased risk of immediate complications, short-term morbidity and mortality, and long-term neurologic and metabolic disorders in adulthood. Previous research has shown that reduced sleep duration is a risk factor for SGA birth. However, only a few studies have evaluated maternal sleep as a risk factor for SGA birth. In the present study, we investigated the relationship between the amount and quality of mothers' sleep and infants' birth weight.

RESULTS

This cohort study (n = 8631) used data from the Japan Environment and Children's Study, an ongoing cohort study that began in January 2011. Data on sleep status (sleep duration and one indicator of sleep quality) and potential confounding factors were recorded. A log-binomial regression model was used to estimate the risk of small for gestational age birth, and the results were expressed as risk ratios and their respective 95% confidence interval. No significant results were observed for sleep duration or tiredness upon waking. Neither the amount nor the quality of mothers' sleep was associated with the risk of small for gestational age birth.

摘要

目的

小于胎龄儿出现即刻并发症、短期发病和死亡以及成年期长期神经和代谢紊乱的风险增加。先前的研究表明,睡眠时间缩短是小于胎龄儿出生的一个风险因素。然而,只有少数研究将母亲睡眠作为小于胎龄儿出生的风险因素进行评估。在本研究中,我们调查了母亲睡眠的量和质量与婴儿出生体重之间的关系。

结果

这项队列研究(n = 8631)使用了来自日本环境与儿童研究的数据,这是一项于2011年1月开始的正在进行的队列研究。记录了睡眠状态(睡眠时间和睡眠质量的一个指标)以及潜在混杂因素的数据。使用对数二项回归模型来估计小于胎龄儿出生的风险,结果以风险比及其各自的95%置信区间表示。在睡眠时间或醒来时的疲劳程度方面未观察到显著结果。母亲睡眠的量和质量均与小于胎龄儿出生的风险无关。

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