低收入和中低收入国家癌症患者的精神障碍：一项系统评价与荟萃分析的研究方案

Psychiatric disorders among people with cancer in low- and lower-middle-income countries: study protocol for a systematic review and meta-analysis.

作者信息

Walker Zoe J, Jones Michael P, Ravindran Arun V

机构信息

Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada.

Centre for Addiction and Mental Health, Toronto, Ontario, Canada.

出版信息

BMJ Open. 2017 Aug 11;7(8):e017043. doi: 10.1136/bmjopen-2017-017043.

DOI:10.1136/bmjopen-2017-017043

PMID:28801432

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5724159/

Abstract

INTRODUCTION

Cancer is a rapidly growing public health problem in low- and lower-middle-income countries (LLMICs). There is evidence from upper-income countries that comorbid mental illness is common and can adversely impact cancer outcomes. Little is known about this burden in LLMICs. This systematic review has two aims. The first is to review the prevalence and patterns of psychiatric comorbidity in adults with cancer in LLMICs. The second is to review psychiatric treatment outcomes in this population.

METHODS AND ANALYSIS

The review will be reported according to the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) guidelines. A systematic search of electronic databases (MEDLINE, PsycInfo, Embase and CINAHL) will be conducted. Studies will be included if they report the prevalence of psychiatric comorbidity, or if they evaluate psychiatric treatment outcomes, in adults with cancer living in LLMICs. The search will be limited to studies published in peer-reviewed journals between March 2002 and March 2017. The reference lists of included studies will be hand searched. Critical appraisal will be performed using Quality Assessment Tools from the National Institute of Health. Pooled prevalence meta-analysis is planned.

ETHICS AND DISSEMINATION

Ethics approval is not required as no primary data will be collected. The results will be presented at conferences and published in a peer-reviewed journal.

SYSTEMATIC REVIEW REGISTRATION

PROSPERO CRD42017057103.

摘要

引言

在低收入和中低收入国家（LLMICs），癌症是一个迅速增长的公共卫生问题。来自高收入国家的证据表明，合并精神疾病很常见，并且会对癌症治疗结果产生不利影响。关于LLMICs中的这种负担，我们知之甚少。本系统评价有两个目的。第一个目的是回顾LLMICs中成年癌症患者精神疾病合并症的患病率和模式。第二个目的是回顾该人群的精神疾病治疗结果。

方法与分析

本评价将按照系统评价与Meta分析的首选报告项目（PRISMA）指南进行报告。将对电子数据库（MEDLINE、PsycInfo、Embase和CINAHL）进行系统检索。如果研究报告了LLMICs中成年癌症患者精神疾病合并症的患病率，或者评估了精神疾病治疗结果，则将其纳入。检索将限于2002年3月至2017年3月期间发表在同行评审期刊上的研究。将手工检索纳入研究的参考文献列表。将使用美国国立卫生研究院的质量评估工具进行批判性评价。计划进行合并患病率Meta分析。