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患者在冠状动脉介入治疗过程中辐射暴露时间的变化:大巴黎地区经皮冠状动脉介入治疗登记研究。

Time-Course Reduction in Patient Exposure to Radiation From Coronary Interventional Procedures: The Greater Paris Area Percutaneous Coronary Intervention Registry.

机构信息

From the Cardiology Department (J.-L.G., B.L.), Emergency Department (S.B.), and SAMU 78 (Y.L.), Versailles Hospital (André Mignot), Le Chesnay, France; Paris Cardiovascular Research Center, INSERM Unit 970, France (N.K., M.T., C.S., X.J.); Cardiology Department, European Georges Pompidou University Hospital (N.K., C.S., X.J.), Cardiology Department, University Hospital Cochin (O.V.), and Cardiology Department, University Hospital Henri Mondor (E.T.), Assistance Publique-Hôpitaux de Paris, France; Université Paris-Descartes, France (N.K., M.T., C.S., X.J.); Agence Régionale de Santé d'Ile-de-France (ARSIF), Paris (S.B., A.L., M.M.); Cardiology Department, Foch Hospital, Suresnes, France (H.B.); Cardiology Department, ICPS, Massy, France (H.B.); Cardiology Department, Institut Mutualiste Montsouris, Paris, France (C.C.); Cardiology Department, ICPS, Quincy sous Sénart, France (P.G.); Cardiology Department, Hôpital d'Instruction des Armées Percy, Clamart, France (F.B.); Cardiology Department, René Dubos Hospital, Pontoise, France (F.F.); and Cardiology Department, Simone Veil Hospital, Eaubonne, France (G.K.).

出版信息

Circ Cardiovasc Interv. 2017 Aug;10(8). doi: 10.1161/CIRCINTERVENTIONS.117.005268.

Abstract

BACKGROUND

The frequency of complex percutaneous coronary interventions (PCIs) has increased in the last few years, with a growing concern on the radiation dose received by the patients. Multicenter data from large unselected populations on patients' radiation doses during coronary angiography (CA) and PCI and temporal trends are lacking. This study sought to evaluate the temporal trends in patients' exposure to radiation from CA and PCI.

METHODS AND RESULTS

Data were taken from the CARDIO-ARSIF registry that prospectively collects data on all CAs and PCIs performed in the 36 catheterization laboratories in the Greater Paris Area, the most populated regions in France with about 12 million inhabitants. Kerma area product and Fluoroscopy time from 152 684 consecutive CAs and 103 177 PCIs performed between 2009 and 2013 were analyzed. A continuous trend for a decrease in median [interquartile range] Kerma area product was observed, from 33 [19-55] Gy cm in 2009 to 27 [16-44] Gy cm in 2013 for CA (<0.0001), and from 73 [41-125] to 55 [31-91] Gy cm for PCI (<0.0001). Time-course differences in Kerma area product remained highly significant after adjustment on Fluoroscopy time, PCI procedure complexity, change of x-ray equipment, and other patient- and procedure-related covariates.

CONCLUSIONS

In a large patient population, a steady temporal decrease in patient radiation exposure during CA and PCI was noted between 2009 and 2013. Kerma area product reduction was consistent in all types of procedure and was independent of patient-related factors and PCI procedure complexity.

摘要

背景

近年来,复杂经皮冠状动脉介入治疗(PCI)的频率有所增加,人们越来越关注患者接受的辐射剂量。目前缺乏关于冠状动脉造影(CA)和 PCI 期间患者辐射剂量的大型、未选择人群的多中心数据以及时间趋势。本研究旨在评估 CA 和 PCI 期间患者辐射暴露的时间趋势。

方法和结果

数据来自 CARDIO-ARSIF 登记处,该登记处前瞻性地收集了法国人口最多的大巴黎地区 36 个导管实验室进行的所有 CA 和 PCI 的数据。在 2009 年至 2013 年期间,分析了 152684 例连续 CA 和 103177 例 PCI 的比释动能面积乘积和透视时间。观察到中位数[四分位间距]比释动能面积乘积呈连续下降趋势,CA 从 2009 年的 33[19-55]Gy·cm降至 2013 年的 27[16-44]Gy·cm(<0.0001),PCI 从 73[41-125]降至 55[31-91]Gy·cm(<0.0001)。在调整透视时间、PCI 程序复杂性、X 射线设备变化以及其他患者和程序相关协变量后,比释动能面积乘积的时间变化仍然具有高度显著性。

结论

在大型患者人群中,2009 年至 2013 年间,CA 和 PCI 期间患者辐射暴露呈持续时间下降趋势。比释动能面积乘积的降低在所有类型的手术中都是一致的,并且独立于患者相关因素和 PCI 程序复杂性。

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