Scalzitti Nicholas, Hansen Shana, Maturo Stephen, Lospinoso Joshua, O'Connor Peter
Department of Otolaryngology-Head and Neck Surgery, San Antonio Uniformed Services Health Education Consortium, San Antonio, TX, United States.
Department of Sleep Medicine, San Antonio Uniformed Services Health Education Consortium, San Antonio, TX, United States.
Int J Pediatr Otorhinolaryngol. 2017 Sep;100:44-51. doi: 10.1016/j.ijporl.2017.06.013. Epub 2017 Jun 16.
Obstructive sleep apnea (OSA) affects 1-5% of pediatric patients. Laboratory polysomnography is expensive, not always available, and is inconvenient for patients. Our study investigates the diagnostic ability of an unattended ambulatory monitor for the diagnosis of pediatric OSA.
A prospective study was conducted in children, ages 2-17. Subjects completed in-lab polysomnography simultaneously with ambulatory monitoring. Caregivers attempted home studies on two subsequent nights to compare the home monitor and the laboratory polysomnogram (PSG).
Thirty-three subjects completed simultaneous laboratory polysomnogram with portable monitoring. Twenty patients completed home studies, with 16 completing 2 nights of monitoring. The measurement of AHI by the portable monitor was different than that obtained by the PSG with statistical significance for the comparisons of PSG vs. In-Lab (p = 0.0026), PSG vs. Home 1 (p = 0.033), and PSG vs. Home 2 (p = 0.033). The sensitivity of the portable monitor for diagnosing OSA was best for the In-lab use at 81%, but only 69% and 70% for the uses at home on the 2 nights respectively. Interestingly, the comparison of AHI and lowest oxygen saturation measurements from the home sleep test in children age 6 and older did not differ significantly from the PSG.
This pilot study demonstrated differences between home sleep testing and in-lab polysomnography for the diagnosis of pediatric sleep apnea. These differences were predominantly found to exist in younger children. Larger prospective studies are needed prior to widespread use, but home studies may alleviate issues of access to care and higher costs of laboratory polysomnography.
阻塞性睡眠呼吸暂停(OSA)影响1%至5%的儿科患者。实验室多导睡眠图检查费用高昂,并非随时可用,且对患者来说不方便。我们的研究调查了一种无人值守的动态监测仪对儿科OSA的诊断能力。
对2至17岁的儿童进行了一项前瞻性研究。受试者在进行动态监测的同时完成了实验室多导睡眠图检查。护理人员在随后的两个晚上尝试进行家庭研究,以比较家庭监测仪和实验室多导睡眠图(PSG)。
33名受试者同时完成了实验室多导睡眠图检查和便携式监测。20名患者完成了家庭研究,其中16名完成了两晚的监测。便携式监测仪测得的呼吸暂停低通气指数(AHI)与PSG测得的不同,PSG与实验室检查(p = 0.0026)、PSG与家庭检查1(p = 0.033)以及PSG与家庭检查2(p = 0.033)的比较具有统计学意义。便携式监测仪诊断OSA的敏感性在实验室使用时最佳,为81%,但在家庭使用的两个晚上分别仅为69%和70%。有趣的是,6岁及以上儿童家庭睡眠测试的AHI和最低血氧饱和度测量值与PSG相比无显著差异。
这项初步研究表明,家庭睡眠测试和实验室多导睡眠图检查在诊断儿科睡眠呼吸暂停方面存在差异。这些差异主要存在于年幼儿童中。在广泛使用之前需要进行更大规模的前瞻性研究,但家庭研究可能会缓解就医问题以及实验室多导睡眠图检查成本较高的问题。