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采用同种异体骨支柱和自体骨联合接骨术治疗22例股骨远端难治性骨不连。

Management of resistant distal femur non-unions with allograft strut and autografts combined with osteosynthesis in a series of 22 patients.

作者信息

Kanakeshwar Raja Bhaskara, Jayaramaraju Dheenadhayalan, Agraharam Devendra, Rajasekaran Shanmuganathan

机构信息

Department of Orthopaedics & Trauma, Ganga Hospital, Mettupalayam Road, Coimbatore, India.

Department of Orthopaedics & Trauma, Ganga Hospital, Mettupalayam Road, Coimbatore, India.

出版信息

Injury. 2017 Aug;48 Suppl 2:S14-S17. doi: 10.1016/S0020-1383(17)30488-6.

Abstract

INTRODUCTION AND PURPOSE

Challenges to the surgeon in managing cases of resistant non-union of the distal femur include poor bone stock, disuse osteopenia and joint contractures. Procedures varying from simple bone grafting to megaprosthesis revision have been described. We successfully managed such cases using our technique of combining cortical allograft struts to augment the defect in the femoral condyle coupled with autogenous iliac crest bone grafting and locking plate osteosynthesis.

MATERIALS AND METHODS

Between April 2012 and May 2014, 22 patients who presented with resistant nonunions of the distal femur following initial surgery were managed using this technique. Cortical allograft struts were taken from the tissue bank of our institution. All patients were followed up post operatively and their time to union was noted. Functional outcome was calculated using LEFS (Lower extremity functional score). The average follow up of all our patients was 24 months.

RESULTS

All patients went on to achieve complete bony union. The average union time was 6.2 months (5 to 8 months). One patient who was a diabetic had superficial infection post operatively which was treated successfully with IV antibiotics. Average knee flexion was 110 degrees (80 to 130 degrees). The mean LEFS score was 72 (59 to 79).

CONCLUSION

Combing a locking plate fixation with the bone grafting technique of using an allograft strut to support the metaphyseal medial bone defect and autografts gives a good union and a good functional outcome in the management of resistant non-unions of the distal femur by enhancing the biology and providing a good structural support to the distal femur.

摘要

引言与目的

外科医生在处理股骨远端难治性骨不连病例时面临诸多挑战,包括骨量不足、废用性骨质减少和关节挛缩。已描述了从简单骨移植到大型假体翻修等各种手术方法。我们采用皮质同种异体骨支柱联合自体髂骨移植及锁定钢板内固定技术成功处理了此类病例,以扩大股骨髁部的骨缺损。

材料与方法

2012年4月至2014年5月,22例初次手术后出现股骨远端难治性骨不连的患者采用该技术进行治疗。皮质同种异体骨支柱取自我们机构的组织库。所有患者术后均进行随访,并记录其骨愈合时间。使用下肢功能评分(LEFS)计算功能结果。所有患者的平均随访时间为24个月。

结果

所有患者均实现了完全骨愈合。平均愈合时间为6.2个月(5至8个月)。1例糖尿病患者术后出现浅表感染,经静脉使用抗生素成功治疗。平均膝关节屈曲度为110度(80至130度)。平均LEFS评分为72分(59至79分)。

结论

通过增强生物学特性并为股骨远端提供良好的结构支撑,将锁定钢板固定与使用同种异体骨支柱支撑干骺端内侧骨缺损及自体骨移植的骨移植技术相结合,在处理股骨远端难治性骨不连时可实现良好的骨愈合和功能结果。

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