INRA-Aquitaine and University of Bordeaux, UMR1332, CS20032, 33882 Villenave d'Ornon, France; INRA-Aquitaine and Bordeaux Science Agro, UMR1391, CS20032, 33882 Villenave d'Ornon, France.
Curr Opin Virol. 2017 Oct;26:112-119. doi: 10.1016/j.coviro.2017.07.030. Epub 2017 Aug 10.
Viruses cause epidemics in all major crops, threatening global food security. The development of efficient and durable resistance able to withstand viral attacks represents a major challenge for agronomy, and relies greatly on the understanding of the molecular dialogue between viral pathogens and their hosts. Research over the last decades provided substantial advances in the field of plant-virus interactions. Remarkably, the advent of studies of plant innate immunity has recently offered new strategies exploitable in the field. This review summarizes the recent breakthroughs that define the mechanisms underlying antiviral innate immunity in plants, and emphasizes the importance of integrating that knowledge into crop improvement actions, particularly by exploiting the insights related to immune receptors.
病毒会在所有主要作物中引发疫情,威胁全球粮食安全。开发能够抵御病毒攻击的高效、持久的抗性是农学面临的重大挑战,这在很大程度上依赖于对病毒病原体与其宿主之间分子对话的理解。过去几十年的研究在植物-病毒相互作用领域取得了重大进展。值得注意的是,植物先天免疫研究的出现最近提供了可在该领域利用的新策略。本文综述了定义植物抗病毒先天免疫机制的最新突破,并强调了将这些知识整合到作物改良行动中的重要性,特别是通过利用与免疫受体相关的见解。