Lipinska-Gediga Małgorzata
Department of Anaesthesiology and Intensive Care, 4th Military Hospital of Wroclaw Faculty of Health Science, Wroclaw Medical University, Poland.
Anaesthesiol Intensive Ther. 2017;49(3):235-240. doi: 10.5603/AIT.2017.0041.
Neutrophils are an key part of the innate immune system in the host's defences against pathogens. Circulating neutrophils are recruited at the sites of infection or sterile inflammation in response to pathogen and host-derived inflammatory mediators. In addition to phagocytosis and degranulation, neutrophils display the release of NETs in order to restrain infection. NETs are able to entrap and kill microbes, and display proinflammatory and prothrombotic properties.
中性粒细胞是宿主抵御病原体的固有免疫系统的关键组成部分。循环中的中性粒细胞会在病原体和宿主来源的炎症介质的作用下，被招募到感染部位或无菌性炎症部位。除了吞噬作用和脱颗粒作用外，中性粒细胞还会释放中性粒细胞胞外陷阱（NETs）以抑制感染。NETs能够捕获并杀死微生物，并具有促炎和促血栓形成的特性。
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