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颈动脉内膜切除术治疗支架内再狭窄:一例病例报告及文献综述

Carotid endarterectomy for in-stent restenosis: a case report and literature review.

作者信息

Xu Baofeng, Liu Rui, Jiao Liqun, Yu Jinlu

机构信息

Department of Neurosurgery, The First Hospital of Jilin University, Changchun, Jilin 130021, P.R. China.

Department of Endocrinology, The Third Hospital of Jilin University, Changchun, Jilin 130021, P.R. China.

出版信息

Biomed Rep. 2017 Aug;7(2):128-132. doi: 10.3892/br.2017.933. Epub 2017 Jun 23.

DOI:10.3892/br.2017.933
PMID:28804624
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5526111/
Abstract

It is relatively difficult to treat restenosis when restenosis occurs following carotid artery stenting. Endarterectomy with simultaneous stent removal is an effective approach when restenosis occurs. The treatment method is still not well known. The present paper reports a case of restenosis after stenting that was treated with endarterectomy with a satisfactory treatment outcome. The patient, a 74-year-old male, underwent stenting 10 months before he was re-hospitalized. He seemed to recover well after stenting until one month before he was re-hospitalized, when he presented symptoms of cerebral ischemia. Imaging examination revealed that in-stent stenosis had reoccurred, with the stenosis degree ranging from 70-99%. He was given endarterectomy treatment, and intra-operative findings showed that the stent grew into a carotid artery plaque and protruded below the adventitia and that the stent lumen was not covered by carotid artery intima. The surgery completely and successfully removed the plaque and the stent, while the adventitia was completely preserved. Follow-up indicated that there was no stenosis in the carotid artery, and the prognosis was good. Relevant literature was also reviewed in this paper, and the authors suggested that carotid artery plaque and stent endarterectomy is beneficial. However, surgical treatment for in-stent stenosis remains a challenging option.

摘要

颈动脉支架置入术后发生再狭窄时,治疗相对困难。当发生再狭窄时,同期取出支架的内膜切除术是一种有效的治疗方法。该治疗方法尚不为人熟知。本文报道了1例支架置入术后再狭窄患者,采用内膜切除术治疗,治疗效果满意。该患者为74岁男性,再次住院前10个月接受了支架置入术。支架置入术后他似乎恢复良好,直到再次住院前1个月出现脑缺血症状。影像学检查显示支架内再狭窄,狭窄程度为70%-99%。他接受了内膜切除术治疗,术中发现支架长入颈动脉斑块并突出至外膜下方,且支架管腔未被颈动脉内膜覆盖。手术完全成功地切除了斑块和支架,同时完整保留了外膜。随访显示颈动脉无狭窄,预后良好。本文还回顾了相关文献,作者认为颈动脉斑块和支架内膜切除术是有益的。然而,支架内狭窄的手术治疗仍然是一个具有挑战性的选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a66b/5526111/11707a2b4f32/br-07-02-0128-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a66b/5526111/ac7fcc32f990/br-07-02-0128-g00.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a66b/5526111/30666fcc5ab3/br-07-02-0128-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a66b/5526111/11707a2b4f32/br-07-02-0128-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a66b/5526111/ac7fcc32f990/br-07-02-0128-g00.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a66b/5526111/30666fcc5ab3/br-07-02-0128-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a66b/5526111/11707a2b4f32/br-07-02-0128-g02.jpg

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本文引用的文献

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Nagoya J Med Sci. 2016 May;78(2):143-9.
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Interventions for Extracranial Carotid Artery Stenosis: An Update.颅外颈动脉狭窄的干预措施:最新进展
Curr Treat Options Cardiovasc Med. 2016 May;18(5):34. doi: 10.1007/s11936-016-0455-9.
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Randomized Trial of Stent versus Surgery for Asymptomatic Carotid Stenosis.无症状性颈动脉狭窄支架治疗与手术治疗随机试验
Influences of Stent Design on In-Stent Restenosis and Major Cardiac Outcomes: A Scoping Review and Meta-Analysis.
支架设计对支架内再狭窄和主要心脏结局的影响:一项范围综述和荟萃分析。
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Current understanding of chronic total occlusion of the internal carotid artery.目前对颈内动脉慢性完全闭塞的认识。
Biomed Rep. 2018 Feb;8(2):117-125. doi: 10.3892/br.2017.1033. Epub 2017 Dec 18.
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Association between age and risk of stroke or death from carotid endarterectomy and carotid stenting: a meta-analysis of pooled patient data from four randomised trials.年龄与颈动脉内膜切除术和颈动脉支架置入术卒中和死亡风险的关系:四项随机试验汇总患者数据的荟萃分析。
Lancet. 2016 Mar 26;387(10025):1305-11. doi: 10.1016/S0140-6736(15)01309-4. Epub 2016 Feb 12.
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Long-term results of drug-eluting balloon angioplasty for treatment of refractory recurrent carotid in-stent restenosis.药物洗脱球囊血管成形术治疗难治性复发性颈动脉支架内再狭窄的长期结果
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Eur J Vasc Endovasc Surg. 2014 Jan;47(1):8-12. doi: 10.1016/j.ejvs.2013.10.011. Epub 2013 Oct 22.