Othman Maha, Kaur Harmanpreet
Department of Biomedical and Molecular Sciences, School of Medicine, Queen's University, 18 Stuart Street, Kingston, ON, Canada, K7L 3N6.
School of Baccalaureate Nursing, St Lawrence College, Kingston, ON, Canada.
Methods Mol Biol. 2017;1646:533-543. doi: 10.1007/978-1-4939-7196-1_39.
Thromboelastography (TEG) has been used for decades to guide transfusion therapy during cardiac and hepatic surgeries. Renewed interest and improved technology have led to wider applications of TEG in other areas of hemostasis. To correctly interpret the data generated and to validate outcomes, it is important to improve the understanding of the differences in the currently available assay procedures, the issues related to sample activation, and the importance of the use of appropriate controls. Current TEG assays use a variety of samples and can vary slightly in the procedures. In this chapter, we very briefly review TEG applications and discuss interpretations, normal ranges, and reference controls, and we explain the method of TEG run using standard citrated native blood samples. We provide detailed technical steps and tips. We discuss precautions and issues related to the assay, which we hope can guide toward better application and data interpretation.
血栓弹力图（TEG）已被用于指导心脏和肝脏手术中的输血治疗数十年。新的兴趣和改进的技术使得TEG在止血的其他领域得到了更广泛的应用。为了正确解释所生成的数据并验证结果，重要的是要更好地理解当前可用检测程序的差异、与样本激活相关的问题以及使用适当对照的重要性。当前的TEG检测使用多种样本，并且程序可能略有不同。在本章中，我们非常简要地回顾TEG的应用，并讨论解读、正常范围和参考对照，我们还将解释使用标准枸橼酸盐抗凝全血样本进行TEG检测的方法。我们提供详细的技术步骤和提示。我们讨论与该检测相关的注意事项和问题，希望能为更好的应用和数据解读提供指导。
