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营养在物质使用障碍康复中的重要性:一项综述。

The importance of nutrition in aiding recovery from substance use disorders: A review.

作者信息

Jeynes Kendall D, Gibson E Leigh

机构信息

Department of Life Sciences, Whitelands College, University of Roehampton, London SW15 4JD, UK.

Department of Psychology, Whitelands College, University of Roehampton, Holybourne Avenue, London SW15 4JD, UK.

出版信息

Drug Alcohol Depend. 2017 Oct 1;179:229-239. doi: 10.1016/j.drugalcdep.2017.07.006. Epub 2017 Aug 4.

Abstract

BACKGROUND

Nutrition is a prerequisite for health; yet, there is no special nutritional assessment or guidance for drug and alcohol dependent individuals, despite the fact that their food consumption is often very limited, risking malnutrition. Further, the premise is examined that malnutrition may promote drug seeking and impede recovery from substance use disorders (SUD).

METHOD

A narrative review addressed the relationship between substance use disorders and nutrition, including evidence for malnutrition, as well as their impact on metabolism and appetite regulation. The implications of the biopsychology of addiction and appetite for understanding the role of nutrition in SUD were also considered.

RESULTS

The literature overwhelmingly finds that subjects with alcohol use disorder (AUD) and drug use disorder (DUD) typically suffer from nutrient deficiencies. These nutrient deficiencies may be complicit in the alcoholic myopathy, osteopenia and osteoporosis, and mood disorders including anxiety and depression, observed in AUD and DUD. These same individuals have also been found to have altered body composition and altered hormonal metabolic regulators. Additionally, brain processes fundamental for survival are stimulated both by food, particularly sweet foods, and by substances of abuse, with evidence supporting confusion (addiction transfer) when recovering from SUD between cravings for a substance and craving for food.

CONCLUSION

Poor nutritional status in AUD and DUD severely impacts their physical and psychological health, which may impede their ability to resist substances of abuse and recover their health. This review contributes to a better understanding of interventions that could best support individuals with substance use disorders.

摘要

背景

营养是健康的前提;然而,对于药物和酒精依赖者却没有特殊的营养评估或指导,尽管他们的食物摄入量往往非常有限,存在营养不良的风险。此外,还探讨了营养不良可能促使药物寻求行为并阻碍物质使用障碍(SUD)康复的假设。

方法

进行一项叙述性综述,阐述物质使用障碍与营养之间的关系,包括营养不良的证据,以及它们对新陈代谢和食欲调节的影响。还考虑了成瘾和食欲的生物心理学对于理解营养在物质使用障碍中的作用的意义。

结果

文献中大量研究发现,酒精使用障碍(AUD)和药物使用障碍(DUD)患者通常存在营养缺乏问题。这些营养缺乏可能与酒精性肌病、骨质减少和骨质疏松以及在酒精使用障碍和药物使用障碍中观察到的包括焦虑和抑郁在内的情绪障碍有关。还发现这些个体的身体成分和激素代谢调节因子发生了改变。此外,食物,特别是甜食,以及滥用物质都会刺激生存所必需的大脑活动,有证据支持在从物质使用障碍康复过程中,对物质的渴望和对食物的渴望之间存在混淆(成瘾转移)。

结论

酒精使用障碍和药物使用障碍患者的营养不良状况严重影响他们的身心健康,这可能会阻碍他们抵制滥用物质和恢复健康的能力。本综述有助于更好地理解哪些干预措施最能支持物质使用障碍患者。

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