Institute of Mental Health, Palmoticeva 37, 11000, Belgrade, Serbia.
School of Medicine, University of Belgrade, Dr Subotica 8, 11000, Belgrade, Serbia.
Sci Rep. 2017 Aug 14;7(1):8105. doi: 10.1038/s41598-017-08706-3.
Drug-induced Extrapyramidal Symptoms Scale (DIEPSS) is developed in the era of second-generation antipsychotics and is suitable for evaluation of the low incidence of extrapyramidal symptoms occurring in the treatment of atypical antipsychotics, as well as the relationship between personal and social functioning. The study was carried out at the Institute of Mental Health in Serbia in 2015 Study used the 127 DIEPSS video clips material, recorded from 1987 till 2015. Four raters performed the assessment simultaneously, individually rating one assigned item immediately after seeing the video clip. For the purpose of evaluating test-retest reliability the second assessment of the same material was performed nine months after the first assessment. Inter-rater reliability was high for each individual item, with ICCs ranging from 0.769 to 0.949. The inter-rater reliability was highest for akathisia item and lowest for dyskinesia. The test-retest reliability was high for each individual item, with ICC ranging from 0.713 to 0.935. The test-retest reliability was highest for bradykinesia item and lowest for dystonia. The Serbian version of DIEPSS has high level of inter-rater and test-retest reliability. High values of concordance rates (ICC > 0.7) for each evaluated individual item suggest that items of DIEPSS are well defined.
药物引起的锥体外系症状量表（DIEPSS）是在第二代抗精神病药物时代开发的，适用于评估非典型抗精神病药物治疗中出现的锥体外系症状的低发生率，以及个人和社会功能之间的关系。该研究于 2015 年在塞尔维亚心理健康研究所进行，研究使用了 127 个 DIEPSS 视频片段材料，这些材料是从 1987 年到 2015 年记录的。四名评估者同时进行评估，在观看视频片段后立即单独评估一个指定的项目。为了评估测试-重测信度，在第一次评估后的九个月对相同的材料进行了第二次评估。每个单项的组内信度都很高，ICC 范围从 0.769 到 0.949。对于静坐不能项目，组内信度最高，对于运动障碍项目，组内信度最低。每个单项的测试-重测信度都很高，ICC 范围从 0.713 到 0.935。对于运动迟缓和运动障碍项目，测试-重测信度最低。DIEPSS 的塞尔维亚语版本具有很高的组内和重测信度。对于每个评估的单项，一致性率（ICC＞0.7）的高值表明 DIEPSS 的项目定义良好。
