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优化用于正电子发射断层扫描(PET)的碲化镉(CdTe)探测器的时间性能。

Optimizing timing performance of CdTe detectors for PET.

作者信息

Nakhostin M

机构信息

Department of Physics, University of Surrey, Guildford GU2 7XH, United Kingdom.

出版信息

Phys Med Biol. 2017 Sep 12;62(19):N485-N505. doi: 10.1088/1361-6560/aa8664.

Abstract

Despite several attractive properties, the poor timing performance of compound semiconductor detectors such as CdTe and CdZnTe has hindered their use in commercial PET imaging systems. The standard method of pulse timing with such detectors is to employ a constant-fraction discriminator at the output of a timing filter which is fed by the pulses from a charge-sensitive preamplifier. The method has led to a time resolution of about 10 ns at full-width at half-maximum (FWHM) with 1 mm thick CdTe detectors. This paper presents a detailed investigation on the parameters limiting the timing performance of Ohmic contact planar CdTe detectors with the standard pulse timing method. The jitter and time-walk errors are studied through simulation and experimental measurements and it is revealed that the best timing results obtained with the standard timing method suffer from a significant loss of coincidence events (~50%). In order to improve the performance of the detectors with full detection efficiency, a new digital pulse timing method based on a simple pattern recognition technique was developed. A time resolution of 3.29  ±  0.10 ns (FWHM) in the energy range of 300-650 keV was achieved with an Ohmic contact planar CdTe detector (5  ×  5  ×  1 mm). The digital pulse processing method was also used to correct for the charge-trapping effect and an improvement in the energy resolution from 4.83  ±  0.66% to 2.780  ±  0.002% (FWHM) at 511 keV was achieved. Further improvement of time resolution through a moderate cooling of the detector and the application of the method to other detector structures are also discussed.

摘要

尽管具有一些吸引人的特性,但碲化镉(CdTe)和碲锌镉(CdZnTe)等化合物半导体探测器较差的定时性能阻碍了它们在商业正电子发射断层扫描(PET)成像系统中的应用。使用此类探测器进行脉冲定时的标准方法是在定时滤波器的输出端采用恒比鉴别器,该滤波器由电荷灵敏前置放大器输出的脉冲驱动。采用这种方法,对于1毫米厚的碲化镉探测器,在半高全宽(FWHM)处可实现约10纳秒的时间分辨率。本文对采用标准脉冲定时方法时限制欧姆接触平面碲化镉探测器定时性能的参数进行了详细研究。通过模拟和实验测量研究了抖动和时间游动误差,结果表明,采用标准定时方法获得的最佳定时结果存在大量符合事件损失(约50%)。为了在保持全探测效率的情况下提高探测器性能,开发了一种基于简单模式识别技术的新型数字脉冲定时方法。使用欧姆接触平面碲化镉探测器(5×5×1毫米)在300 - 650 keV能量范围内实现了3.29±0.10纳秒(FWHM)的时间分辨率。该数字脉冲处理方法还用于校正电荷俘获效应,在511 keV时能量分辨率从4.83±0.66%提高到了2.780±0.002%(FWHM)。还讨论了通过适度冷却探测器进一步提高时间分辨率以及将该方法应用于其他探测器结构的情况。

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