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硅水凝胶隐形眼镜作为LASEK手术后绷带镜的临床研究。

Clinic study on silicone hydrogel contact lenses used as bandage contact lenses after LASEK surgery.

作者信息

Qu Xiao-Mei, Dai Jin-Hui, Jiang Zhen-Ying, Qian Yi-Feng

机构信息

Department of Ophthalmology, Eye and ENT Hospital Affiliated to Fudan University, Shanghai 200031, China.

出版信息

Int J Ophthalmol. 2011;4(3):314-8. doi: 10.3980/j.issn.2222-3959.2011.03.22. Epub 2011 Jun 18.

Abstract

AIM

To compare the clinical performance of two types of silicon hydrogel contact lenses used as bandage lenses after LASEK surgery.

METHODS

A prospective, double-masked study was conducted on 42 eyes of 21 patients who received binocular LASEK surgeries. The interocular difference in spherical equivalent power was less than -1.50D. Patients were randomly assigned to wear Galyfilcon A (Lens A) bandage contact lens in one eye and Balafilcon A (Lens B) in the fellow eye after the surgery. The responses to a subjective questionnaire on comfort of wearing, corneal epithelial status, conjunctival hyperemia, limbal neovascularization, lens fitting and contact lens debris were assessed 1 and 5 days postoperatively. Corneal endothelium was assessed before and 5 days after the surgery upon bandage lens removal.

RESULTS

There was no difference between the two groups in terms of conjunctival hyperemia, limbal neovascularization, contact lens fitting, corneal epithelial status, corneal endothelium cell density (CD) and endothelium cell size (CS) at any postoperative visit. Complaints of discomfort, including foreign body sensation, pain and intolerance were statistically more among Lens B wearers at any postoperative visit (P<0.05). Lens B appeared to attract much more debris than Lens A at the 5-day post-operative follow-up visit (P<0.01).

CONCLUSION

The two types of silicon hydrogel lenses investigated in this study demonstrated similar clinical performance in terms of corneal responses and lens fitting. However, Lens A showed a better performance in terms of comfort of wearing and deposit resistance.

摘要

目的

比较两种硅水凝胶隐形眼镜作为准分子激光上皮下角膜磨镶术(LASEK)术后绷带镜的临床性能。

方法

对21例行双眼LASEK手术的患者的42只眼进行了一项前瞻性、双盲研究。双眼等效球镜度差异小于-1.50D。患者术后随机分配一只眼佩戴加丽菲康A(镜片A)绷带接触镜,另一只眼佩戴百超菲康A(镜片B)。在术后1天和5天评估关于佩戴舒适度、角膜上皮状态、结膜充血、角膜缘新生血管、镜片适配和隐形眼镜碎片的主观问卷回复情况。在术后移除绷带镜前及移除后5天评估角膜内皮情况。

结果

在任何术后访视中,两组在结膜充血、角膜缘新生血管、隐形眼镜适配、角膜上皮状态、角膜内皮细胞密度(CD)和内皮细胞大小(CS)方面均无差异。在任何术后访视中,镜片B佩戴者中包括异物感、疼痛和不耐受等不适主诉在统计学上更多(P<0.05)。在术后5天的随访中,镜片B似乎比镜片A吸引更多的碎片(P<0.01)。

结论

本研究中所研究的两种硅水凝胶镜片在角膜反应和镜片适配方面表现出相似的临床性能。然而,镜片A在佩戴舒适度和抗沉淀方面表现更好。

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