Hipsley AnnMarie, Ma David Hui-Kang, Sun Chi-Chin, Jackson Mitchell A, Goldberg Daniel, Hall Brad
Ace Vision Group Inc, 39655 Eureka Drive, Newark, CA 94560 USA.
Department of Ophthalmology, Chang Gung Memorial Hospital, Kweishan, Taoyuan Taiwan.
Eye Vis (Lond). 2017 Jun 16;4:15. doi: 10.1186/s40662-017-0081-y. eCollection 2017.
To evaluate the effects on near and intermediate visual performance after bilateral Laser Anterior Ciliary Excision (LaserACE) procedure.
LaserACE surgery was performed using the VisioLite 2.94 μm erbium: yttrium-aluminum-garnet (Er:YAG) ophthalmic laser system in 4 oblique quadrants on the sclera over the ciliary muscle in 3 critical zones of physiological importance (over the ciliary muscles and posterior zonules) with the aim to improve natural dynamic accommodative forces. LaserACE was performed on 26 patients (52 eyes). Outcomes were analyzed using visual acuity testing, Randot stereopsis, and the CatQuest 9SF patient survey.
Binocular uncorrected near visual acuity (UNVA) improved from +0.20 ± 0.16 logMAR preoperatively, to +0.12 ± 0.14 logMAR at 24 months postoperatively ( = 0.0014). There was no statistically significant loss in distance corrected near visual acuity (DCNVA). Binocular DCNVA improved from +0.21 ± 0.17 logMAR preoperatively, to +0.11 ± 0.12 logMAR at 24 months postoperatively ( = 0.00026). Stereoacuity improved from 74.8 ± 30.3 s of arc preoperatively, to 58.8 ± 22.9 s of arc at 24 months postoperatively ( = 0.012). There were no complications such as persistent hypotony, cystoid macular edema, or loss of best-corrected visual acuity (BCVA). Patients surveyed indicated reduced difficulty in areas of near vision, and were overall satisfied with the procedure.
Preliminary results of the LaserACE procedure show promising results for restoring visual performance for near and intermediate visual tasks without compromising distance vision and without touching the visual axis. The visual function and visual acuity improvements had clinical significance. Patient satisfaction was high postoperatively and sustained over 24 months.
NCT01491360 (https://clinicaltrials.gov/ct2/show/NCT01491360). Registered 22 November 2011.
评估双侧激光睫状体前切除术（LaserACE）术后对近视力和中视力的影响。
使用VisioLite 2.94μm铒：钇铝石榴石（Er:YAG）眼科激光系统在巩膜上睫状肌上方的4个斜象限，于3个具有重要生理意义的关键区域（睫状肌和后晶状体悬韧带上方）进行LaserACE手术，目的是增强自然动态调节力。对26例患者（52只眼）实施了LaserACE手术。使用视力测试、Randot立体视检查和CatQuest 9SF患者调查问卷对结果进行分析。
双眼未矫正近视力（UNVA）从术前的+0.20±0.16对数最小分辨角（logMAR）提高到术后24个月时的+0.12±0.14 logMAR（P = 0.0014）。矫正近视力（DCNVA）无统计学意义的下降。双眼DCNVA从术前的+0.21±0.17 logMAR提高到术后24个月时的+0.11±0.12 logMAR（P = 0.00026）。立体视锐度从术前的74.8±30.3弧秒提高到术后24个月时的58.8±22.9弧秒（P = 0.012）。未出现持续性低眼压、黄斑囊样水肿或最佳矫正视力（BCVA）丧失等并发症。接受调查的患者表示近视力方面的困难有所减轻，总体对该手术满意。
LaserACE手术的初步结果表明，在不影响远视力且不触及视轴的情况下，该手术在恢复近视力和中视力视觉任务的视觉性能方面显示出有前景的结果。视觉功能和视力的改善具有临床意义。术后患者满意度较高，且在24个月内持续保持。
NCT01491360（https://clinicaltrials.gov/ct2/show/NCT01491360）。于2011年11月22日注册。
