Xu Ye, Li Meiyan, Yao Peijun, Wei Ruoyan, Zhou Xingtao
Department of Ophthalmology, Eye & ENT Hospital, Fudan University, Shanghai, China.
NHC Key Laboratory of Myopia (Fudan University), Key Laboratory of Myopia, Chinese Academy of Medical Sciences, Shanghai, China.
Ann Transl Med. 2020 Oct;8(19):1224. doi: 10.21037/atm-20-2141.
To investigate the visual outcomes over 1 year after laser anterior ciliary excision (LaserACE) procedure for presbyopic subjects.
A prospective, non-randomized, non-comparative study. Eight emmetropic eyes of four patients with presbyopia were included in this study. All eyes were treated with the LaserACE procedure using the VisioLite erbium-YAG laser (Ace Vision Group, USA). Subjects were assessed preoperatively and at 1 day, 1 week, 1 month, 3 months, 6 months, and 1 year postoperatively. Outcome measures included questionnaires, visual acuity, manifest refraction, pupil size, keratometry, reading prescription, and intraocular pressure.
Binocular distance corrected intermediate visual acuity (DCIVA) had improved from 0.33±0.12 logMAR to 0.12±0.12 logMAR after 6 months (P<0.05) and 0.13±0.12 logMAR after 12 months postoperatively (P<0.01). Binocular distance corrected near visual acuity (DCNVA) improved from 0.41±0.10 logMAR to 0.24±0.12 logMAR after 6 months (P<0.05) and 0.26±0.09 log MAR after 12 months postoperatively (P<0.05). An average decrease of 0.91±0.28 D in the reading prescription at a 40 cm reading distance was observed and remained stable over 12 months (P<0.05). There were no significant differences in manifest refraction, uncorrected distance visual acuity (UDVA), corneal curvature, high order aberrations, pupil size compared with preoperative and 6 months as well as 12 months postoperative visits (P>0.05).
The LaserACE procedure is shown to be safe and efficient for presbyopia correction without influencing distance vision or visual quality. However, its mechanism and long-term effects need further validation.
研究老视患者行激光睫状肌前徙术（LaserACE）后1年以上的视觉效果。
一项前瞻性、非随机、非对照研究。本研究纳入了4例老视患者的8只正视眼。所有眼睛均使用VisioLite铒钇铝石榴石激光（美国Ace Vision Group）进行LaserACE手术。对受试者在术前以及术后1天、1周、1个月、3个月、6个月和1年进行评估。观察指标包括问卷调查、视力、显验光、瞳孔大小、角膜曲率、阅读验光处方和眼压。
双眼距离矫正中间视力（DCIVA）在术后6个月时从0.33±0.12 logMAR提高到0.12±0.12 logMAR（P<0.05），术后12个月时为0.13±0.12 logMAR（P<0.01）。双眼距离矫正近视力（DCNVA）在术后6个月时从0.41±0.10 logMAR提高到0.24±0.12 logMAR（P<0.05），术后12个月时为0.26±0.09 logMAR（P<0.05）。在40 cm阅读距离处，阅读验光处方平均降低了0.91±0.28 D，并在12个月内保持稳定（P<0.05）。与术前以及术后6个月和12个月的随访相比，显验光、未矫正远视力（UDVA）、角膜曲率、高阶像差、瞳孔大小均无显著差异（P>0.05）。
LaserACE手术在矫正老视方面安全有效，且不影响远视力或视觉质量。然而，其机制和长期效果需要进一步验证。
