Barbosa Adriana Agostini, Figueiredo Ana Cristina Silva, Palhao Miller Pereira, Viana Joao Henrique Moreira, Fernandes Carlos Antonio Carvalho
Universidade José do Rosário Vellano, Rodovia MG 179, Km 0, Campus Universitário, Alfenas, MG, 37130-000, Brazil.
Biotran Biotecnologia e Treinamento em Reprodução Animal, Rua Tatuin 447, Alfenas, MG, 37130-000, Brazil.
Trop Anim Health Prod. 2017 Dec;49(8):1779-1781. doi: 10.1007/s11250-017-1361-1. Epub 2017 Aug 15.
Brucellosis is an infectious and contagious disease that profoundly impacts public health. However, in many countries, disease prevention is restricted to the vaccination of calves, and there is no prophylactic strategy for pregnant heifers and cows. The aim of this study was to evaluate the safety of the rough strain vaccine against brucellosis in pregnant cattle. Crossbred cows (N = 96) at three gestational periods (early, mid, or late pregnancy) were randomly allocated into the vaccine treatment group or to the control group. We then compared the percentage of pregnancies reaching full term, live calves 60 days after delivery, and seropositive calves. There was no effect of vaccination in any of the gestational periods on the evaluation endpoints. In conclusion, vaccination against brucellosis with the rough strain is safe for pregnant cattle at all gestational periods.
布鲁氏菌病是一种对公共卫生有深远影响的传染性疾病。然而，在许多国家，疾病预防仅限于对犊牛进行疫苗接种，对于怀孕的小母牛和母牛没有预防性策略。本研究的目的是评估粗糙菌株疫苗对怀孕母牛预防布鲁氏菌病的安全性。将处于三个妊娠期（妊娠早期、中期或晚期）的杂交奶牛（N = 96）随机分为疫苗治疗组或对照组。然后我们比较了足月妊娠的百分比、分娩后60天存活的犊牛以及血清阳性犊牛的情况。在任何妊娠期进行疫苗接种对评估终点均无影响。总之，用粗糙菌株疫苗对布鲁氏菌病进行预防接种对所有妊娠期的怀孕母牛都是安全的。
