Department of Chemical Engineering, Delft University of Technology, van der Maasweg 9, Delft, 2629, HZ, The Netherlands.
Angew Chem Int Ed Engl. 2017 Nov 20;56(47):14923-14927. doi: 10.1002/anie.201706272. Epub 2017 Sep 12.
A generic method is used for compartmentalization of supramolecular hydrogels by using water-in-water emulsions based on aqueous multi-phase systems (AMPS). By forming the low-molecular-weight hydrogel throughout all phases of all-aqueous emulsions, distinct, micro-compartmentalized materials were created. This structuring approach offers control over the composition of each type of the compartments by directing the partitioning of objects to be encapsulated. Moreover, this method allows for barrier-less, dynamic exchange of even large hydrophilic solutes (MW≈60 kDa) between separate aqueous compartments. These features are expected to find use in the fields of, for instance, micro-structured catalysts, templating, and tissue engineering.
本研究采用水包水乳液法，基于双水相体系（aqueous multi-phase systems，AMPS）对超分子水凝胶进行分隔。通过在全水乳液的所有相中形成低分子量水凝胶，制备出具有独特微分隔的材料。该结构方法通过引导被包封物体的分配，实现对每种隔室组成的控制。此外，该方法允许在单独的水隔室之间进行无阻碍的、大亲水溶质（MW≈60 kDa）的动态交换。这些特性有望在微结构化催化剂、模板和组织工程等领域得到应用。
