Centre for the AIDS Programme of Research in South Africa (CAPRISA), University of KwaZulu-Natal, Durban, South Africa.
Department of Medical Microbiology, University of KwaZulu-Natal, Durban, South Africa.
Genome Med. 2017 Aug 17;9(1):74. doi: 10.1186/s13073-017-0469-2.
Advances in molecular tools to characterize the microbiome have led to the discovery of unique roles for microbes in human disease. Findings that the female genital microbiome can influence HIV acquisition and prevention emphasize the importance of microbiome analysis in clinical trials that assess the efficacy of HIV prevention interventions.
分子工具的进步使人们能够深入了解微生物组,从而发现微生物在人类疾病中的独特作用。研究发现,女性生殖道微生物组可以影响 HIV 的感染和预防,这强调了在评估 HIV 预防干预措施效果的临床试验中进行微生物组分析的重要性。