Kerwin William S, Miller Zach, Yuan Chun
University of Washington Vascular Imaging Lab, Department of Radiology, 850 Republican Street, Seattle, WA 98109.
University of Washington Vascular Imaging Lab, Department of Radiology, 850 Republican Street, Seattle, WA 98109.
Semin Vasc Surg. 2017 Mar;30(1):54-61. doi: 10.1053/j.semvascsurg.2017.04.009. Epub 2017 Apr 27.
The emergence of the concept of high-risk atherosclerotic plaque has led to considerable interest in noninvasive imaging techniques to identify high-risk features before clinical sequelae. For plaques in the carotid arteries, magnetic resonance imaging has undergone considerable histologic validation to link imaging features to indicators of plaque instability, including plaque burden, intraplaque hemorrhage, fibrous cap disruption, lipid rich necrotic core, and calcification. Recently introduced imaging technologies, especially those focused on three-dimensional imaging sequences, are now poised for integration into the clinical workup of patients with suspected carotid atherosclerosis. The purpose of this article is to review the carotid plaque magnetic resonance imaging techniques that are most ready for integration into the clinic.
高危动脉粥样硬化斑块概念的出现引发了人们对非侵入性成像技术的浓厚兴趣，以便在临床后遗症出现之前识别高危特征。对于颈动脉斑块，磁共振成像已经历了大量组织学验证，以将成像特征与斑块不稳定性指标联系起来，这些指标包括斑块负荷、斑块内出血、纤维帽破裂、富含脂质的坏死核心和钙化。最近引入的成像技术，尤其是那些专注于三维成像序列的技术，现在已准备好整合到疑似颈动脉粥样硬化患者的临床检查中。本文的目的是回顾最适合整合到临床中的颈动脉斑块磁共振成像技术。
