Physical Activity Epidemiology Laboratory, Exercise Psychology Laboratory, Department of Health, Exercise Science and Recreation Management, The University of Mississippi, United States.
Jackson Heart Study Vanguard Center of Oxford, Physical Activity Epidemiology Laboratory, Exercise Psychology Laboratory, Department of Health, Exercise Science and Recreation Management, The University of Mississippi, United States.
Eur J Intern Med. 2018 Jan;47:32-35. doi: 10.1016/j.ejim.2017.08.012. Epub 2017 Aug 14.
We evaluated the specific differential association between non-bouted, lifestyle physical activities (vs. structured exercise; i.e., bouted physical activity) on retinopathy prevalence among a national sample of the broader U.S. adult population.
Data from the 2005-2006 National Health and Nutrition Examination Survey (NHANES) was used to identify 1501 adults, between 40 and 85years. Bouted and non-bouted physical activities were assessed using objective accelerometer monitoring. A 10-minute bout was defined as 10+ consecutive minutes above the moderate-to-vigorous physical activity (MVPA) cut-point, with the allowance of 1-2-minute interruption intervals. Non-bout MVPA was determined by the number of MVPA minutes not accrued in a bout. Participants were screened for non-proliferative retinopathy using Early Treatment Diabetic Retinopathy Study grading criteria, as well as objective retinal imaging assessments using the Canon Non-Mydriatic Retinal Camera CR6-45NM. Individuals were excluded if they had been diagnosed with coronary artery disease, congestive heart failure, heart attack or stroke.
Participants with worse retinopathy engaged in less bouted and non-bouted physical activity, had a higher BMI and were more likely to have diabetes and hypertension. For every 1min/day increase in non-bouted MVPA, participants had a 7% reduced odds of moderate-to-severe retinopathy compared to no retinopathy (OR=0.93; 95% CI: 0.87-0.99; P=0.04); results were similar in an unadjusted model (OR=0.93; 95% CI: 0.89-0.97; P=0.007). Bouted MVPA was not associated with retinopathy prevalence in the multivariate model.
In this nationally representative sample of adults, those who engaged in non-bouted physical activity had reduced odds of a diagnosis of moderate-to-severe retinopathy.
我们评估了非定时、生活方式体力活动（与定时锻炼相比，即定时体力活动）与更广泛的美国成年人群体的视网膜病变患病率之间的特定差异关联。
使用 2005-2006 年国家健康和营养检查调查（NHANES）的数据，确定了 1501 名年龄在 40 至 85 岁之间的成年人。使用客观加速度计监测来评估定时和非定时体力活动。将 10 分钟的定时活动定义为 10 分钟以上连续时间超过中度至剧烈体力活动（MVPA）切点，允许有 1-2 分钟的中断间隔。非定时 MVPA 通过未定时活动中累计的 MVPA 分钟数来确定。使用早期糖尿病视网膜病变研究分级标准以及使用佳能非散瞳视网膜相机 CR6-45NM 进行的客观视网膜成像评估来筛查非增殖性视网膜病变。如果参与者被诊断患有冠状动脉疾病、充血性心力衰竭、心脏病发作或中风，则将其排除在外。
视网膜病变较严重的参与者进行的定时和非定时体力活动较少，体重指数较高，且更有可能患有糖尿病和高血压。与无视网膜病变相比，非定时 MVPA 每增加 1 分钟/天，参与者患中度至重度视网膜病变的几率降低 7%（OR=0.93；95%CI：0.87-0.99；P=0.04）；在未调整的模型中结果相似（OR=0.93；95%CI：0.89-0.97；P=0.007）。定时 MVPA 与多变量模型中的视网膜病变患病率无关。
在这个具有全国代表性的成年人样本中，进行非定时体力活动的参与者患中度至重度视网膜病变的几率降低。
