Sinnott Sarah-Jo, Bennett Kathleen, Cahir Caitriona
Department of Non-communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, Keppel St, London, WC1E 7HT, UK.
Division of Population Health Sciences, Royal College of Surgeons Ireland, Dublin, Ireland.
Eur J Clin Pharmacol. 2017 Nov;73(11):1449-1455. doi: 10.1007/s00228-017-2310-7. Epub 2017 Aug 17.
Administrative health data, such as pharmacy claims data, present a valuable resource for conducting pharmacoepidemiological and health services research. Often, data are available for whole populations allowing population level analyses. Moreover, their routine collection ensures that the data reflect health care utilisation in the real-world setting compared to data collected in clinical trials.
The Irish Health Service Executive-Primary Care Reimbursement Service (HSE-PCRS) community pharmacy claims database is described. The availability of demographic variables and drug-related information is discussed. The strengths and limitations associated using this database for conducting research are presented, in particular, internal and external validity. Examples of recently conducted research using the HSE-PCRS pharmacy claims database are used to illustrate the breadth of its use.
The HSE-PCRS national pharmacy claims database is a large, high-quality, valid and accurate data source for measuring drug exposure in specific populations in Ireland. The main limitation is the lack of generalisability for those aged <70 years and the lack of information on indication or outcome.
行政卫生数据，如药房报销数据，是开展药物流行病学和卫生服务研究的宝贵资源。通常，这些数据涵盖整个人口，可进行人群水平的分析。此外，其常规收集确保数据反映现实环境中的医疗保健利用情况，与临床试验中收集的数据相比。
描述了爱尔兰卫生服务执行局 - 初级保健报销服务（HSE - PCRS）社区药房报销数据库。讨论了人口统计学变量和药物相关信息的可用性。介绍了使用该数据库进行研究的优势和局限性，特别是内部和外部有效性。使用最近使用HSE - PCRS药房报销数据库进行的研究示例来说明其使用的广度。
HSE - PCRS国家药房报销数据库是用于测量爱尔兰特定人群药物暴露的大型、高质量、有效且准确的数据源。主要局限性是对于70岁以下人群缺乏普遍性，以及缺乏关于适应症或结局的信息。
