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1968 - 2013年美国人类肠道沙门氏菌都柏林血清型感染的流行病学

Epidemiology of Salmonella enterica Serotype Dublin Infections among Humans, United States, 1968-2013.

作者信息

Harvey R Reid, Friedman Cindy R, Crim Stacy M, Judd Michael, Barrett Kelly A, Tolar Beth, Folster Jason P, Griffin Patricia M, Brown Allison C

出版信息

Emerg Infect Dis. 2017 Sep;23(9):1493-501. doi: 10.3201/eid2309.170136.

Abstract

Salmonella enterica serotype Dublin is a cattle-adapted bacterium that typically causes bloodstream infections in humans. To summarize demographic, clinical, and antimicrobial drug resistance characteristics of human infections with this organism in the United States, we analyzed data for 1968-2013 from 5 US surveillance systems. During this period, the incidence rate for infection with Salmonella Dublin increased more than that for infection with other Salmonella. Data from 1 system (FoodNet) showed that a higher percentage of persons with Salmonella Dublin infection were hospitalized and died during 2005-2013 (78% hospitalized, 4.2% died) than during 1996-2004 (68% hospitalized, 2.7% died). Susceptibility data showed that a higher percentage of isolates were resistant to >7 classes of antimicrobial drugs during 2005-2013 (50.8%) than during 1996-2004 (2.4%).

摘要

肠炎沙门氏菌都柏林血清型是一种适应于牛的细菌,通常会导致人类发生血液感染。为总结美国人类感染这种细菌的人口统计学、临床和抗菌药物耐药性特征,我们分析了来自美国5个监测系统的1968 - 2013年的数据。在此期间,都柏林沙门氏菌感染的发病率比其他沙门氏菌感染的发病率增长得更多。来自一个系统(食品网)的数据显示,与1996 - 2004年(68%住院,2.7%死亡)相比,2005 - 2013年期间都柏林沙门氏菌感染患者住院和死亡的比例更高(78%住院,4.2%死亡)。药敏数据显示,与1996 - 2004年(2.4%)相比,2005 - 2013年期间更高比例的分离株对超过7类抗菌药物耐药(50.8%)。

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