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与赤狐脑炎相关的A组轮状病毒

Group A Rotavirus Associated with Encephalitis in Red Fox.

作者信息

Busi Chiara, Martella Vito, Papetti Alice, Sabelli Cristiano, Lelli Davide, Alborali G Loris, Gibelli Lucia, Gelmetti Daniela, Lavazza Antonio, Cordioli Paolo, Boniotti M Beatrice

出版信息

Emerg Infect Dis. 2017 Sep;23(9):1535-1538. doi: 10.3201/eid2309.170158.

DOI:10.3201/eid2309.170158
PMID:28820385
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5572894/
Abstract

In 2011, a group A rotavirus was isolated from the brain of a fox with encephalitis and neurologic signs, detected by rabies surveillance in Italy. Intracerebral inoculation of fox brain homogenates into mice was fatal. Genome sequencing revealed a heterologous rotavirus of avian origin, which could provide a model for investigating rotavirus neurovirulence.

摘要

2011年，在意大利的狂犬病监测中，从一只患有脑炎和神经症状的狐狸大脑中分离出一株A组轮状病毒。将狐狸脑匀浆脑内接种到小鼠体内是致命的。基因组测序显示这是一种禽源异源轮状病毒，可为研究轮状病毒神经毒力提供一个模型。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/360d/5572894/fb2878599b99/17-0158-F2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/360d/5572894/d1a041f49212/17-0158-F1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/360d/5572894/fb2878599b99/17-0158-F2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/360d/5572894/d1a041f49212/17-0158-F1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/360d/5572894/fb2878599b99/17-0158-F2.jpg

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