Heart. 2018 Jan;104(2):96-102. doi: 10.1136/heartjnl-2017-311579. Epub 2017 Aug 20.
Acute stress-induced (takotsubo) cardiomyopathy has a dramatic clinical presentation, mimicking an acute myocardial infarction and is triggered by intense emotional or physical stress. In this paper, we review the current state of knowledge of the mechanistic physiology underlying the left ventricular ballooning. The pathophysiology of the recovery from this acute heart failure syndrome is presented. The short-term and long-term outlook puts this new syndrome on a different perspective compared with recently held views. Current knowledge on susceptibility and predisposition already define distinctive characteristics of patients with takotsubo compared with myocardial infarction. Gaps in knowledge and future directions of research are identified in order to best direct efforts for identifying specific therapies for this condition, in the acute setting, to mitigate postacute symptoms or to prevent recurrences, none of which exist.
应激性心肌病（心尖球囊综合征）具有显著的临床表现，类似于急性心肌梗死，由强烈的情绪或身体应激引起。本文综述了目前对左心室球囊样变的机械生理学基础的认识。本文还介绍了这种急性心力衰竭综合征恢复的病理生理学。与最近的观点相比，这种新综合征的短期和长期预后有了不同的认识。目前关于易感性和倾向性的知识已经确定了心尖球囊综合征患者与心肌梗死患者的不同特征。为了明确这种疾病的特定治疗方法，确定急性缓解期、减轻亚急性期症状或预防复发的最佳方向，本文确定了目前存在的知识空白和未来的研究方向。目前，尚无针对这种疾病的特定治疗方法。
