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致密胶原蛋白中解离和重组的软骨微粒诱导局部人骨髓间充质干细胞分化。

Dissociated and Reconstituted Cartilage Microparticles in Densified Collagen Induce Local hMSC Differentiation.

作者信息

Novak Tyler, Seelbinder Benjamin, Twitchell Celina M, Voytik-Harbin Sherry L, Neu Corey P

机构信息

Weldon School of Biomedical Engineering, Purdue University, West Lafayette, IN 47907, USA.

出版信息

Adv Funct Mater. 2016 Aug 9;26(30):5427-5436. doi: 10.1002/adfm.201601877. Epub 2016 Jul 1.

DOI:10.1002/adfm.201601877
PMID:28824356
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5560495/
Abstract

Hybrid usage of native tissue signals and the engineering control of collagen matrices show the ability to induce local infiltration and differentiation of hMSCs. Additionally, the solid cartilage microparticles inhibit bulk cell-mediated contraction of the composite.

摘要

天然组织信号的混合使用以及胶原基质的工程控制显示出诱导人骨髓间充质干细胞局部浸润和分化的能力。此外，固态软骨微粒可抑制复合材料中大量细胞介导的收缩。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbe7/5560495/73ee8fc8efe8/nihms837121f6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbe7/5560495/38d31bd878d7/nihms837121f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbe7/5560495/12c8f344067b/nihms837121f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbe7/5560495/0fb7bbbd693d/nihms837121f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbe7/5560495/ff90998d2a06/nihms837121f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbe7/5560495/3d063a84319b/nihms837121f5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbe7/5560495/73ee8fc8efe8/nihms837121f6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbe7/5560495/38d31bd878d7/nihms837121f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbe7/5560495/12c8f344067b/nihms837121f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbe7/5560495/0fb7bbbd693d/nihms837121f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbe7/5560495/ff90998d2a06/nihms837121f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbe7/5560495/3d063a84319b/nihms837121f5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbe7/5560495/73ee8fc8efe8/nihms837121f6.jpg

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