大肠杆菌K12谷氨酰胺合成酶操纵子的完整核苷酸序列。
The complete nucleotide sequence of the glnALG operon of Escherichia coli K12.
作者信息
Miranda-Ríos J, Sánchez-Pescador R, Urdea M, Covarrubias A A
出版信息
Nucleic Acids Res. 1987 Mar 25;15(6):2757-70. doi: 10.1093/nar/15.6.2757.
Abstract
The nucleotide sequence of the E. coli glnALG operon has been determined. The glnL (ntrB) and glnG (ntrC) genes present a high homology, at the nucleotide and aminoacid levels, with the corresponding genes of Klebsiella pneumoniae. The predicted aminoacid sequence for glutamine synthetase allowed us to locate some of the enzyme domains. The structure of this operon is discussed.
摘要
已确定大肠杆菌谷氨酰胺合成酶操纵子（glnALG operon）的核苷酸序列。谷氨酰胺合成酶调节基因（glnL，即ntrB基因）和谷氨酰胺合成酶激活蛋白基因（glnG，即ntrC基因）在核苷酸和氨基酸水平上与肺炎克雷伯菌的相应基因具有高度同源性。谷氨酰胺合成酶的预测氨基酸序列使我们能够定位该酶的一些结构域。本文讨论了该操纵子的结构。
相似文献
1
The complete nucleotide sequence of the glnALG operon of Escherichia coli K12.大肠杆菌K12谷氨酰胺合成酶操纵子的完整核苷酸序列。
Nucleic Acids Res. 1987 Mar 25;15(6):2757-70. doi: 10.1093/nar/15.6.2757.
2
Identification and regulation of the glnL operator-promoter of the complex glnALG operon of Escherichia coli.大肠杆菌复杂的谷氨酰胺合成酶基因操纵子（glnALG operon）中谷氨酰胺合成酶基因L（glnL）操纵子-启动子的鉴定与调控
J Bacteriol. 1984 Oct;160(1):379-84. doi: 10.1128/jb.160.1.379-384.1984.
3
Role of glnB and glnD gene products in regulation of the glnALG operon of Escherichia coli.谷氨酰胺B和谷氨酰胺D基因产物在大肠杆菌谷氨酰胺合成酶操纵子调节中的作用。
J Bacteriol. 1985 Nov;164(2):816-22. doi: 10.1128/jb.164.2.816-822.1985.
4
Expression of glnA in Escherichia coli is regulated at tandem promoters.大肠杆菌中谷氨酰胺合成酶基因（glnA）的表达受串联启动子调控。
Proc Natl Acad Sci U S A. 1985 Apr;82(7):1979-83. doi: 10.1073/pnas.82.7.1979.
5
Nucleotide sequence of the glnA-glnL intercistronic region of Escherichia coli.大肠杆菌谷氨酰胺合成酶基因（glnA）与谷氨酰胺合成酶基因操纵子阻遏蛋白基因（glnL）间区的核苷酸序列。
Gene. 1985;37(1-3):91-9. doi: 10.1016/0378-1119(85)90261-6.
6
Role of the Escherichia coli glnALG operon in regulation of ammonium transport.大肠杆菌谷氨酰胺合成酶基因操纵子在铵转运调节中的作用。
J Bacteriol. 1986 Apr;166(1):281-4. doi: 10.1128/jb.166.1.281-284.1986.
7
Regulation at the glnL-operator-promoter of the complex glnALG operon of Escherichia coli.大肠杆菌复杂的谷氨酰胺合成酶操纵子（glnALG operon）在谷氨酰胺合成酶基因（glnL）的操纵子-启动子区域的调控。
J Bacteriol. 1983 Mar;153(3):1247-51. doi: 10.1128/jb.153.3.1247-1251.1983.
8
The ntr genes of Escherichia coli activate the hut and nif operons of Klebsiella pneumoniae.大肠杆菌的ntr基因激活肺炎克雷伯菌的hut和nif操纵子。
Gene. 1982 Jul-Aug;19(1):109-16. doi: 10.1016/0378-1119(82)90195-0.
9
Fine-structure deletion map and complementation analysis of the glnA-glnL-glnG region in Escherichia coli.大肠杆菌中谷氨酰胺合成酶基因（glnA）-谷氨酰胺转运蛋白基因（glnL）-谷氨酰胺基因激活蛋白基因（glnG）区域的精细结构缺失图谱及互补分析
J Bacteriol. 1982 Jun;150(3):1302-13. doi: 10.1128/jb.150.3.1302-1313.1982.
10
[Characterization of the glnA-glnG region of Escherichia coli K12].[大肠杆菌K12中谷氨酰胺合成酶基因（glnA）-谷氨酰胺合成酶激活蛋白基因（glnG）区域的特征分析]
Bol Estud Med Biol. 1983 Jul-Oct;32(7-8 Suppl 1):299-307.
引用本文的文献
1
Protection Elicited by Glutamine Auxotroph of .由……的谷氨酰胺营养缺陷型引发的保护作用
Vaccines (Basel). 2025 Mar 26;13(4):353. doi: 10.3390/vaccines13040353.
2
PmrA/PmrB Two-Component System Regulation of Expression in PAO1.PmrA/PmrB双组分系统对PAO1中基因表达的调控
Front Microbiol. 2018 Jan 15;8:2690. doi: 10.3389/fmicb.2017.02690. eCollection 2017.
3
Nitrogen assimilation in Escherichia coli: putting molecular data into a systems perspective.大肠杆菌中的氮同化：将分子数据置于系统视角下。
Microbiol Mol Biol Rev. 2013 Dec;77(4):628-95. doi: 10.1128/MMBR.00025-13.
4
Lipase expression in Pseudomonas alcaligenes is under the control of a two-component regulatory system.产碱假单胞菌中的脂肪酶表达受双组分调节系统的控制。
Appl Environ Microbiol. 2008 Mar;74(5):1402-11. doi: 10.1128/AEM.01632-07. Epub 2008 Jan 11.
5
Two-component response regulators of Vibrio fischeri: identification, mutagenesis, and characterization.费氏弧菌的双组分反应调节因子：鉴定、诱变及特性研究
J Bacteriol. 2007 Aug;189(16):5825-38. doi: 10.1128/JB.00242-07. Epub 2007 Jun 22.
6
Sigma54 enhancer binding proteins and Myxococcus xanthus fruiting body development.σ54增强子结合蛋白与粘球菌子实体发育
J Bacteriol. 2004 Jul;186(13):4361-8. doi: 10.1128/JB.186.13.4361-4368.2004.
7
Roles of rpoN, fliA, and flgR in expression of flagella in Campylobacter jejuni.rpoN、fliA和flgR在空肠弯曲菌鞭毛表达中的作用。
J Bacteriol. 2001 May;183(9):2937-42. doi: 10.1128/JB.183.9.2937-2942.2001.
8
Cloning and random mutagenesis of the Erwinia herbicola tyrR gene for high-level expression of tyrosine phenol-lyase.用于酪氨酸酚裂解酶高水平表达的草生欧文氏菌tyrR基因的克隆与随机诱变
Appl Environ Microbiol. 2000 Nov;66(11):4764-71. doi: 10.1128/AEM.66.11.4764-4771.2000.
9
A sigma(54) activator protein necessary for spore differentiation within the fruiting body of Myxococcus xanthus.一种对于黄色粘球菌子实体中孢子分化所必需的σ（54）激活蛋白。
J Bacteriol. 2000 May;182(9):2438-44. doi: 10.1128/JB.182.9.2438-2444.2000.
10
Linkage map of Escherichia coli K-12, edition 10: the traditional map.大肠杆菌K-12连锁图谱，第10版：传统图谱。
Microbiol Mol Biol Rev. 1998 Sep;62(3):814-984. doi: 10.1128/MMBR.62.3.814-984.1998.
本文引用的文献
1
Isolation of the nitrogen assimilation regulator NR(I), the product of the glnG gene of Escherichia coli.分离出氮同化调节剂 NR(I)，它是大肠杆菌 glnG 基因的产物。
Proc Natl Acad Sci U S A. 1983 Sep;80(18):5554-8. doi: 10.1073/pnas.80.18.5554.
2
A new model for nitrogen control.一种新的氮控制模型。
Nature. 1982 Jun 3;297(5865):362-3. doi: 10.1038/297362a0.
3
Buffer gradient gels and 35S label as an aid to rapid DNA sequence determination.缓冲液梯度凝胶和35S标记辅助快速DNA序列测定。
Proc Natl Acad Sci U S A. 1983 Jul;80(13):3963-5. doi: 10.1073/pnas.80.13.3963.
4
Evidence for use of rare codons in the dnaG gene and other regulatory genes of Escherichia coli.大肠杆菌dnaG基因及其他调控基因中稀有密码子使用的证据。
Proc Natl Acad Sci U S A. 1983 Feb;80(3):687-91. doi: 10.1073/pnas.80.3.687.
5
New M13 vectors for cloning.用于克隆的新型M13载体。
Methods Enzymol. 1983;101:20-78. doi: 10.1016/0076-6879(83)01005-8.
6
Tandem promoters determine regulation of the Klebsiella pneumoniae glutamine synthetase (glnA) gene.串联启动子决定肺炎克雷伯菌谷氨酰胺合成酶（glnA）基因的调控。
Nucleic Acids Res. 1984 Oct 25;12(20):7811-30. doi: 10.1093/nar/12.20.7811.
7
Identification and regulation of the glnL operator-promoter of the complex glnALG operon of Escherichia coli.大肠杆菌复杂的谷氨酰胺合成酶基因操纵子（glnALG operon）中谷氨酰胺合成酶基因L（glnL）操纵子-启动子的鉴定与调控
J Bacteriol. 1984 Oct;160(1):379-84. doi: 10.1128/jb.160.1.379-384.1984.
8
Evidence that nitrogen regulatory gene ntrC of Salmonella typhimurium is transcribed from the glnA promoter as well as from a separate ntr promoter.有证据表明，鼠伤寒沙门氏菌的氮调节基因ntrC是从谷氨酰胺合成酶基因（glnA）启动子以及一个独立的ntr启动子转录而来的。
Mol Gen Genet. 1984;193(1):135-42. doi: 10.1007/BF00327426.
9
Nucleotide sequence of the glnA control region of Escherichia coli.大肠杆菌谷氨酰胺合成酶基因（glnA）调控区的核苷酸序列。
Mol Gen Genet. 1983;190(1):171-5. doi: 10.1007/BF00330342.
10
The product of glnL is not essential for regulation of bacterial nitrogen assimilation.谷氨酰胺合成酶基因（glnL）的产物对于细菌氮同化的调节并非必不可少。
J Bacteriol. 1983 Apr;154(1):516-9. doi: 10.1128/jb.154.1.516-519.1983.
Zotero 插件