痴呆行为和心理症状的决定因素：证据的范围综述
Determinants of behavioral and psychological symptoms of dementia: A scoping review of the evidence.
作者信息
Kolanowski Ann, Boltz Marie, Galik Elizabeth, Gitlin Laura N, Kales Helen C, Resnick Barbara, Van Haitsma Kimberly S, Knehans Amy, Sutterlin Jane E, Sefcik Justine S, Liu Wen, Petrovsky Darina V, Massimo Lauren, Gilmore-Bykovskyi Andrea, MacAndrew Margaret, Brewster Glenna, Nalls Vycki, Jao Ying-Ling, Duffort Naomi, Scerpella Danny
机构信息
College of Nursing, Penn State, University Park, PA.
College of Nursing, Penn State, University Park, PA.
出版信息
Nurs Outlook. 2017 Sep-Oct;65(5):515-529. doi: 10.1016/j.outlook.2017.06.006. Epub 2017 Jun 16.
BACKGROUND
Behavioral and psychological symptoms of dementia (BPSD) are prevalent in people with neurodegenerative diseases.
PURPOSE
In this scoping review the Kales, Gitlin and Lykestos framework is used to answer the question: What high quality evidence exists for the patient, caregiver and environmental determinants of five specific BPSD: aggression, agitation, apathy, depression and psychosis?
METHOD
An a priori review protocol was developed; 692 of 6013 articles retrieved in the search were deemed eligible for review. Gough's Weight of Evidence Framework and the Cochrane Collaboration's tool for assessing risk of bias were used. The findings from 56 high quality/low bias articles are summarized.
DISCUSSION
Each symptom had its own set of determinants, but many were common across several symptoms: neurodegeneration, type of dementia, severity of cognitive impairments, and declining functional abilities, and to a lesser extent, caregiver burden and communication.
CONCLUSION
Research and policy implications are relevant to the National Plan to Address Alzheimer's Disease.
背景
痴呆的行为和心理症状（BPSD）在神经退行性疾病患者中普遍存在。
目的
在本范围综述中，使用卡莱斯、吉特林和莱凯斯托斯框架来回答以下问题：关于五种特定的BPSD（攻击行为、激越、冷漠、抑郁和精神病）的患者、照料者及环境决定因素，有哪些高质量证据？
方法
制定了一个预先设定的综述方案；在检索出的6013篇文章中，有692篇被认为符合综述条件。使用了高夫证据权重框架和 Cochrane 协作网评估偏倚风险的工具。总结了56篇高质量/低偏倚文章的研究结果。
讨论
每种症状都有其自身的一组决定因素，但许多因素在几种症状中是共有的：神经退行性变、痴呆类型、认知障碍的严重程度和功能能力下降，以及在较小程度上，照料者负担和沟通。
结论
研究和政策意义与《应对阿尔茨海默病国家计划》相关。
Zotero 插件