Laboratoire de Physique de la Matière Vivante, Ecole Polytechnique Fédérale de Lausanne (EPFL), 1015 Lausanne, Switzerland; Plateforme de Morphologie, Faculté de Médecine, Université de Lausanne, Bugnion 9, 1005 Lausanne, Switzerland.
Laboratoire de Physique de la Matière Vivante, Ecole Polytechnique Fédérale de Lausanne (EPFL), 1015 Lausanne, Switzerland.
Semin Cell Dev Biol. 2018 Jan;73:177-187. doi: 10.1016/j.semcdb.2017.08.032. Epub 2017 Aug 19.
Atomic force microscopy is nowadays a well-established technique that permits the investigation of numerous parameters of living matter. In particular, it allows the exploration of the mechanical properties of living organisms in almost physiological conditions. Here, we focus on the use of this technology to review recent contributions that relates the physiology and pathology of bacteria, yeast, plant and mammalian cells to their nano-mechanical properties.
原子力显微镜是一种成熟的技术，可用于研究生命物质的诸多参数。特别是，它可以在几乎生理条件下探索生物组织的力学特性。在这里，我们主要关注这项技术的应用，以综述与细菌、酵母、植物和哺乳动物细胞的生理学和病理学相关的最新研究进展，以及它们的纳米力学特性。
