Granström G, Sterner G, Nord C E, Granström M
J Infect Dis. 1987 Jun;155(6):1210-4. doi: 10.1093/infdis/155.6.1210.
During the period 1975-1985, 35 women with serology- or culture-confirmed pertussis at the time of labor were admitted to the Danderyd Hospital (Danderyd, Sweden). In 32 cases, the mothers were allowed to nurse their newborns while receiving erythromycin therapy. Erythromycin prophylaxis was given to 28 newborns. None of the newborns developed clinical or laboratory signs of whooping cough. The therapy was well tolerated by the newborns and did not affect the microflora in the gut. Maternal antibodies to pertussis toxin and to the filamentous hemagglutinin were found in cord blood, and levels decreased during the follow-up period. The study demonstrated that mothers with pertussis can safely be allowed to nurse their infants if both receive erythromycin.
在1975年至1985年期间，35名在分娩时血清学或培养确诊为百日咳的女性被收治于丹德吕德医院（瑞典丹德吕德）。其中32例产妇在接受红霉素治疗时被允许哺乳其新生儿。28名新生儿接受了红霉素预防治疗。没有新生儿出现百日咳的临床或实验室体征。新生儿对该治疗耐受性良好，且未影响肠道微生物群。在脐带血中发现了母体针对百日咳毒素和丝状血凝素的抗体，且在随访期间抗体水平下降。该研究表明，如果母亲和婴儿都接受红霉素治疗，患有百日咳的母亲可以安全地哺乳其婴儿。
