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日本妇产科学会妇科肿瘤学委员会关于日本遗传性乳腺癌和卵巢癌综合征治疗现状的实况调查问卷最终报告。

Final report of the Committee on Gynecologic Oncology, the Japan Society of Obstetrics and Gynecology, on a fact-finding questionnaire on the status of treatment of hereditary breast and ovarian cancer syndrome in Japan.

作者信息

Satoh Toyomi, Takamatsu Kiyoshi, Takeshima Nobuhiro, Kobayashi Hiroshi, Aoki Daisuke, Suzuki Nao

机构信息

Department of Obstetrics and Gynecology, Faculty of Medicine, University of Tsukuba, Ibaraki, Japan.

Department of Obstetrics and Gynecology, Tokyo Dental College Ichikawa General Hospital, Chiba, Japan.

出版信息

J Obstet Gynaecol Res. 2017 Sep;43(9):1377-1380. doi: 10.1111/jog.13409. Epub 2017 Aug 17.

Abstract

Hereditary breast and ovarian cancer syndrome (HBOC) is a hereditary tumor that can be definitively diagnosed by detection of germline mutation of the BRCA1 or BRCA2 gene. The HBOC Public Awareness and Management Sub-committee of the Tumor Committee, Japan Society of Obstetrics and Gynecology carried out a fact-finding survey on the status of treatment of HBOC in Japan. The directors of medical specialty teaching facilities were notified of the questionnaire by post, with the request for one respondent per facility. The response period was from 8 July 2014 to 31 March 2015. Of the 678 facilities that were asked to compete the questionnaire, 341 (50.3%) responded. The responses are shown in the respective tables. For questions with free responses, similar answers have been grouped together, and the written answers have been freely translated. Based on these results, the Japan Society of Obstetrics and Gynecology considers that the 14 conditions, including consultations by specialist staff, must be met before risk-reducing salpingo-oophorectomy is carried out.

摘要

遗传性乳腺癌和卵巢癌综合征(HBOC)是一种遗传性肿瘤,可通过检测BRCA1或BRCA2基因的种系突变来明确诊断。日本妇产科学会肿瘤委员会的HBOC公众认知与管理小组委员会对日本HBOC的治疗现状进行了一项实情调查。通过邮寄方式向各医学专科教学机构的负责人发送了调查问卷,并要求每个机构选派一名受访者作答。调查的回复期为2014年7月8日至2015年3月31日。在被要求填写调查问卷的678家机构中,有341家(50.3%)作出了回复。回复情况列于各表格中。对于开放式问题,相似的答案已进行归类整理,书面回答也已进行了意译。基于这些结果,日本妇产科学会认为,在实施降低风险的输卵管卵巢切除术之前,必须满足包括由专科人员进行会诊在内的14项条件。

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