Institute of Materials, École Polytechnique Fédérale de Lausanne (EPFL), Station 12, 1015, Lausanne, Switzerland.
Institute of Chemical Sciences and Engineering, École Polytechnique Fédérale de Lausanne (EPFL), Station 6, 1015, Lausanne, Switzerland.
Angew Chem Int Ed Engl. 2017 Oct 16;56(43):13521-13525. doi: 10.1002/anie.201708190. Epub 2017 Sep 14.
Ligand exchange reactions are used to achieve nanoparticles coated with a mixture of ligand molecules. Currently, nothing is known on the evolution of the morphology of the ligand shell during the reaction. Here, we use a recently developed method (based on MALDI-TOF) to follow the evolution of the ligand shell composition and morphology during the reaction. We observe the expected evolution in composition and we find that the ligand shell starts as a random mixture and gradually evolves towards a patchy morphology. When the composition has reached a plateau (i.e. when the reaction is generally assumed to be finished), the ligand shell morphology keeps evolving for days, slowly approaching its equilibrium configuration.
配体交换反应被用于实现被混合配体分子覆盖的纳米颗粒。目前，对于配体壳在反应过程中形态的演变还一无所知。在这里，我们使用一种新开发的方法（基于 MALDI-TOF）来跟踪反应过程中配体壳组成和形态的演变。我们观察到预期的组成演变，并且发现配体壳首先是随机混合物，然后逐渐演变成斑驳形态。当组成达到平台期（即通常认为反应已经完成时）时，配体壳形态会继续演变数天，缓慢接近其平衡构型。
