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糖瘾:它是真实存在的吗?一篇叙述性综述。

Sugar addiction: is it real? A narrative review.

机构信息

Saint Luke's Mid America Heart Institute, Kansas, USA.

Lahey Health and the Wilson Institute of Neurobiology, Burlington, USA.

出版信息

Br J Sports Med. 2018 Jul;52(14):910-913. doi: 10.1136/bjsports-2017-097971. Epub 2017 Aug 23.

DOI:10.1136/bjsports-2017-097971
PMID:28835408
Abstract

In animal studies, sugar has been found to produce more symptoms than is required to be considered an addictive substance. Animal data has shown significant overlap between the consumption of added sugars and drug-like effects, including bingeing, craving, tolerance, withdrawal, cross-sensitisation, cross-tolerance, cross-dependence, reward and opioid effects. Sugar addiction seems to be dependence to the natural endogenous opioids that get released upon sugar intake. In both animals and humans, the evidence in the literature shows substantial parallels and overlap between drugs of abuse and sugar, from the standpoint of brain neurochemistry as well as behaviour.

摘要

在动物研究中,糖被发现产生的症状比被认为是成瘾物质所需的症状还要多。动物数据显示,添加糖的消耗与类似药物的效果之间存在显著重叠,包括狂欢、渴望、耐受性、戒断、交叉敏感、交叉耐受、交叉依赖、奖励和阿片样作用。糖成瘾似乎是对糖摄入时释放的天然内源性阿片类物质的依赖。从脑神经化学和行为的角度来看,文献中的证据表明,滥用药物和糖之间存在大量的相似之处和重叠。

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