• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

小分子 GTP 酶、核仁 GTP 结合蛋白 1（NOG1）在植物先天免疫中具有新的作用。

The small GTPase, nucleolar GTP-binding protein 1 (NOG1), has a novel role in plant innate immunity.

机构信息

Noble Research Institute, LLC, Ardmore, Oklahoma, USA.

Gulf Coast Research and Education Center, Institute of Food and Agricultural Science, University of Florida, Balm, Florida, USA.

出版信息

Sci Rep. 2017 Aug 23;7(1):9260. doi: 10.1038/s41598-017-08932-9.

DOI:10.1038/s41598-017-08932-9
PMID:28835689
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5569028/
Abstract

Plant defense responses at stomata and apoplast are the most important early events during plant-bacteria interactions. The key components for the signaling of stomatal defense and nonhost resistance have not been fully characterized. Here we report the newly identified small GTPase, Nucleolar GTP-binding protein 1 (NOG1), functions for plant immunity against bacterial pathogens. Virus-induced gene silencing of NOG1 compromised nonhost resistance in N. benthamiana and tomato. Comparative genomic analysis showed that two NOG1 copies are present in all known plant species: NOG1-1 and NOG1-2. Gene downregulation and overexpression studies of NOG1-1 and NOG1-2 in Arabidopsis revealed the novel function of these genes in nonhost resistance and stomatal defense against bacterial pathogens, respectively. Specially, NOG1-2 regulates guard cell signaling in response to biotic and abiotic stimuli through jasmonic acid (JA)- and abscisic acid (ABA)-mediated pathways. The results here provide valuable information on the new functional role of small GTPase, NOG1, in guard cell signaling and early plant defense in response to bacterial pathogens.

摘要

植物在气孔和质外体中的防御反应是植物与细菌相互作用过程中最重要的早期事件。气孔防御和非寄主抗性信号转导的关键成分尚未完全阐明。在这里，我们报告了新鉴定的小 GTPase，核仁 GTP 结合蛋白 1（NOG1），在植物对细菌病原体的免疫中发挥作用。NOG1 的病毒诱导基因沉默削弱了 N. benthamiana 和番茄中的非寄主抗性。比较基因组分析表明，所有已知植物物种中都存在两个 NOG1 拷贝：NOG1-1 和 NOG1-2。拟南芥中 NOG1-1 和 NOG1-2 的基因下调和过表达研究揭示了这些基因在非寄主抗性和气孔防御细菌病原体方面的新功能。特别是，NOG1-2 通过茉莉酸（JA）和脱落酸（ABA）介导的途径调节保卫细胞信号转导以响应生物和非生物刺激。这些结果为小 GTPase，NOG1 在响应细菌病原体的保卫细胞信号转导和早期植物防御中的新功能作用提供了有价值的信息。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb8f/5569028/1753d908d28d/41598_2017_8932_Fig7_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb8f/5569028/6bcf156a8ccb/41598_2017_8932_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb8f/5569028/a6130ec830a7/41598_2017_8932_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb8f/5569028/203bdb40bf7e/41598_2017_8932_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb8f/5569028/3279e3cabcdd/41598_2017_8932_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb8f/5569028/1e20107aca40/41598_2017_8932_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb8f/5569028/098d30382e24/41598_2017_8932_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb8f/5569028/1753d908d28d/41598_2017_8932_Fig7_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb8f/5569028/6bcf156a8ccb/41598_2017_8932_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb8f/5569028/a6130ec830a7/41598_2017_8932_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb8f/5569028/203bdb40bf7e/41598_2017_8932_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb8f/5569028/3279e3cabcdd/41598_2017_8932_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb8f/5569028/1e20107aca40/41598_2017_8932_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb8f/5569028/098d30382e24/41598_2017_8932_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb8f/5569028/1753d908d28d/41598_2017_8932_Fig7_HTML.jpg

相似文献

1
The small GTPase, nucleolar GTP-binding protein 1 (NOG1), has a novel role in plant innate immunity.小分子 GTP 酶、核仁 GTP 结合蛋白 1（NOG1）在植物先天免疫中具有新的作用。
Sci Rep. 2017 Aug 23;7(1):9260. doi: 10.1038/s41598-017-08932-9.
2
Nucleolar GTP-Binding Protein 1-2 (NOG1-2) Interacts with Jasmonate-ZIMDomain Protein 9 (JAZ9) to Regulate Stomatal Aperture during Plant Immunity.核仁 GTP 结合蛋白 1-2（NOG1-2）与茉莉酸-ZIM 结构域蛋白 9（JAZ9）相互作用，以在植物免疫过程中调节气孔开度。
Int J Mol Sci. 2018 Jun 30;19(7):1922. doi: 10.3390/ijms19071922.
3
Nonhost resistance against bacterial pathogens: retrospectives and prospects.非寄主对细菌病原体的抗性：回顾与展望。
Annu Rev Phytopathol. 2013;51:407-27. doi: 10.1146/annurev-phyto-082712-102319.
4
Phytosterols play a key role in plant innate immunity against bacterial pathogens by regulating nutrient efflux into the apoplast.植物甾醇通过调节养分向质外体的外排，在植物先天免疫抵抗细菌病原体方面发挥着关键作用。
Plant Physiol. 2012 Apr;158(4):1789-802. doi: 10.1104/pp.111.189217. Epub 2012 Jan 31.
5
14-3-3 proteins in plant-pathogen interactions.植物-病原体相互作用中的14-3-3蛋白
Mol Plant Microbe Interact. 2015 May;28(5):511-8. doi: 10.1094/MPMI-10-14-0322-CR.
6
GENERAL CONTROL NONREPRESSIBLE4 Degrades 14-3-3 and the RIN4 Complex to Regulate Stomatal Aperture with Implications on Nonhost Disease Resistance and Drought Tolerance.一般控制不可抑制 4 降解 14-3-3 和 RIN4 复合物来调节气孔开度，这对非寄主疾病抗性和耐旱性有影响。
Plant Cell. 2017 Sep;29(9):2233-2248. doi: 10.1105/tpc.17.00070. Epub 2017 Aug 30.
7
Plant microRNAs: Front line players against invading pathogens.植物 microRNAs：抵御入侵病原体的前线战士。
Microb Pathog. 2018 May;118:9-17. doi: 10.1016/j.micpath.2018.03.008. Epub 2018 Mar 7.
8
Host versus nonhost resistance: distinct wars with similar arsenals.宿主对非宿主抗性：武器库相似的不同战争。
Phytopathology. 2015 May;105(5):580-7. doi: 10.1094/PHYTO-11-14-0298-RVW.
9
Plastic Transcriptomes Stabilize Immunity to Pathogen Diversity: The Jasmonic Acid and Salicylic Acid Networks within the Arabidopsis/ Pathosystem.塑料转录组稳定了对病原体多样性的免疫：拟南芥/病原体系统中的茉莉酸和水杨酸网络。
Plant Cell. 2017 Nov;29(11):2727-2752. doi: 10.1105/tpc.17.00348. Epub 2017 Oct 17.
10
Two Chloroplast-Localized Proteins: AtNHR2A and AtNHR2B, Contribute to Callose Deposition During Nonhost Disease Resistance in Arabidopsis.两个定位于叶绿体的蛋白：AtNHR2A 和 AtNHR2B，在拟南芥非寄主疾病抗性过程中有助于胼胝质的沉积。
Mol Plant Microbe Interact. 2018 Dec;31(12):1280-1290. doi: 10.1094/MPMI-04-18-0094-R. Epub 2018 Oct 8.

引用本文的文献

1
Mapping the Architecture of Protein Complexes in Using Cross-Linking Mass Spectrometry.利用交联质谱法绘制蛋白质复合物的结构
bioRxiv. 2025 Jul 21:2025.04.28.651104. doi: 10.1101/2025.04.28.651104.
2
Ribosome biogenesis in plants requires the nuclear envelope and mitochondria localized OPENER complex.植物中的核糖体生物合成需要定位于核膜和线粒体的OPENER复合体。
Nat Commun. 2025 Aug 7;16(1):7301. doi: 10.1038/s41467-025-62652-7.
3
Physiological and molecular characteristics associated with the anti-senescence in Abel.与阿贝尔抗衰老相关的生理和分子特征。

本文引用的文献

1
An Arabidopsis Plasma Membrane Proton ATPase Modulates JA Signaling and Is Exploited by the Pseudomonas syringae Effector Protein AvrB for Stomatal Invasion.一种拟南芥质膜质子ATP酶调节茉莉酸信号传导，并被丁香假单胞菌效应蛋白AvrB用于气孔入侵。
Plant Cell. 2015 Jul;27(7):2032-41. doi: 10.1105/tpc.15.00466. Epub 2015 Jul 21.
2
A sophisticated network of signaling pathways regulates stomatal defenses to bacterial pathogens.一个复杂的信号通路网络调节气孔对细菌病原体的防御。
Mol Plant. 2015 Apr;8(4):566-81. doi: 10.1016/j.molp.2014.10.012. Epub 2014 Dec 17.
3
Recruitment of PLANT U-BOX13 and the PI4Kβ1/β2 phosphatidylinositol-4 kinases by the small GTPase RabA4B plays important roles during salicylic acid-mediated plant defense signaling in Arabidopsis.
Photosynthetica. 2024 Feb 5;62(1):102-111. doi: 10.32615/ps.2024.003. eCollection 2024.
4
Genome-wide association study of traits in sacred lotus uncovers MITE-associated variants underlying stamen petaloid and petal number variations.对荷花性状的全基因组关联研究揭示了与雄蕊瓣化和花瓣数量变异相关的微小反向重复转座元件（MITE）关联变异。
Front Plant Sci. 2022 Sep 23;13:973347. doi: 10.3389/fpls.2022.973347. eCollection 2022.
5
Engineering Ribosomes to Alleviate Abiotic Stress in Plants: A Perspective.工程化改造核糖体以缓解植物非生物胁迫：一个视角
Plants (Basel). 2022 Aug 12;11(16):2097. doi: 10.3390/plants11162097.
6
Activation of the VQ Motif-Containing Protein Gene Compromised Nonhost Resistance of to Pathogens.含VQ基序蛋白基因的激活损害了对病原体的非寄主抗性。
Plants (Basel). 2022 Mar 24;11(7):858. doi: 10.3390/plants11070858.
7
Overexpression of Arabidopsis nucleolar GTP-binding 1 (NOG1) proteins confers drought tolerance in rice.拟南芥核仁 GTP 结合蛋白 1（NOG1）的过表达赋予水稻抗旱性。
Plant Physiol. 2022 Jun 1;189(2):988-1004. doi: 10.1093/plphys/kiac078.
8
Genetic Insight Into the Insect Resistance in Bread Wheat Exploiting the Untapped Natural Diversity.利用未开发的自然多样性对面包小麦抗虫性的遗传洞察。
Front Genet. 2022 Feb 11;13:828905. doi: 10.3389/fgene.2022.828905. eCollection 2022.
9
Piriformospora indica recruits host-derived putrescine for growth promotion in plants.内脐蠕孢菌招募植物来源的腐胺促进植物生长。
Plant Physiol. 2022 Mar 28;188(4):2289-2307. doi: 10.1093/plphys/kiab536.
10
Comparative RNA-Seq analysis unfolds a complex regulatory network imparting yellow mosaic disease resistance in mungbean [Vigna radiata (L.) R. Wilczek].比较 RNA-Seq 分析揭示了赋予绿豆[Vigna radiata（L.）R. Wilczek]抗黄花叶病的复杂调控网络。
PLoS One. 2021 Jan 12;16(1):e0244593. doi: 10.1371/journal.pone.0244593. eCollection 2021.
小GTP酶RabA4B对植物U盒蛋白13（PLANT U - BOX13）和磷脂酰肌醇 - 4激酶PI4Kβ1/β2的招募在拟南芥水杨酸介导的植物防御信号传导过程中发挥重要作用。
Plant Cell. 2015 Jan;27(1):243-61. doi: 10.1105/tpc.114.134262. Epub 2015 Jan 29.
4
Host versus nonhost resistance: distinct wars with similar arsenals.宿主对非宿主抗性：武器库相似的不同战争。
Phytopathology. 2015 May;105(5):580-7. doi: 10.1094/PHYTO-11-14-0298-RVW.
5
Evidence for lateral gene transfer (LGT) in the evolution of eubacteria-derived small GTPases in plant organelles.真细菌来源的小GTP酶在植物细胞器进化过程中的横向基因转移（LGT）证据。
Front Plant Sci. 2014 Dec 11;5:678. doi: 10.3389/fpls.2014.00678. eCollection 2014.
6
Rho family GTPase-dependent immunity in plants and animals.植物和动物中依赖Rho家族GTP酶的免疫反应
Front Plant Sci. 2014 Oct 14;5:522. doi: 10.3389/fpls.2014.00522. eCollection 2014.
7
Light-dependent expression of flg22-induced defense genes in Arabidopsis.拟南芥中 flg22 诱导防御基因的光依赖性表达。
Front Plant Sci. 2014 Oct 9;5:531. doi: 10.3389/fpls.2014.00531. eCollection 2014.
8
A mitogen-activated protein kinase cascade module, MKK3-MPK6 and MYC2, is involved in blue light-mediated seedling development in Arabidopsis.一个丝裂原活化蛋白激酶级联模块，即MKK3-MPK6和MYC2，参与拟南芥蓝光介导的幼苗发育。
Plant Cell. 2014 Aug;26(8):3343-57. doi: 10.1105/tpc.114.128702. Epub 2014 Aug 19.
9
Gate control: guard cell regulation by microbial stress.门控：微生物胁迫对保卫细胞的调节。
New Phytol. 2014 Sep;203(4):1049-1063. doi: 10.1111/nph.12916. Epub 2014 Jul 8.
10
Intervention of Phytohormone Pathways by Pathogen Effectors.病原菌效应蛋白对植物激素信号通路的干预
Plant Cell. 2014 Jun;26(6):2285-2309. doi: 10.1105/tpc.114.125419. Epub 2014 Jun 10.