与异位胃黏膜（胃入口斑）相关的高位食管蹼形成：一个小病例系列
High oesophageal web formation in association with heterotopic gastric mucosa (the gastric inlet patch): a small case series.
作者信息
Ainley Eric J
出版信息
Frontline Gastroenterol. 2011 Apr;2(2):117-123. doi: 10.1136/fg.2010.002311. Epub 2011 Jan 12.
Abstract
BACKGROUND
Upper oesophageal webs or rings have rarely been reported in association with heterotopic gastric mucosa (HGM).
OBJECTIVE
To describe the finding of oesophageal webs in association with HGM.
DESIGN
Small case series.
SETTING
Patients presenting with dysphagia to an open access hospital dysphagia clinic.
PATIENTS
Six cases were found.
INTERVENTIONS
Symptomatic improvement is demonstrated with oesophageal dilatation in symptomatic patients.
MAIN OUTCOME MEASUREMENTS
Symptomatic improvement.
RESULTS
The six cases which are described here demonstrate that a web or ring exactly matches the distribution of the heterotopic mucosa, can occur at both proximal and distal squamo-columnar junctions and the inlet patches may be multiple with multiple rings. A radiological double web sign is described.
LIMITATIONS
A rare condition with a small number of patients.
CONCLUSIONS
Effective treatment can be by oesophageal dilatation and acid suppression. The cause of web formation is thought to be due to heterotopic acid production and is analogous to the Schatzki ring.
摘要
背景
上食管蹼或环与异位胃黏膜（HGM）相关的报道很少。
目的
描述与HGM相关的食管蹼的发现。
设计
小病例系列。
地点
在一家开放式医院吞咽困难诊所就诊的吞咽困难患者。
患者
发现6例。
干预措施
有症状的患者通过食管扩张症状得到改善。
主要观察指标
症状改善。
结果
这里描述的6例病例表明，蹼或环与异位黏膜的分布完全匹配，可发生在近端和远端鳞状柱状交界处，入口斑可能有多个且伴有多个环。描述了一种放射学双蹼征。
局限性
一种罕见疾病，患者数量少。
结论
有效的治疗方法可以是食管扩张和抑酸。蹼形成的原因被认为是由于异位酸的产生，类似于沙茨基环。
相似文献
1
High oesophageal web formation in association with heterotopic gastric mucosa (the gastric inlet patch): a small case series.与异位胃黏膜（胃入口斑）相关的高位食管蹼形成：一个小病例系列
Frontline Gastroenterol. 2011 Apr;2(2):117-123. doi: 10.1136/fg.2010.002311. Epub 2011 Jan 12.
2
Prevalence and clinical features of heterotopic gastric mucosa in the upper oesophagus (inlet patch).食管上段异位胃黏膜（入口斑）的患病率及临床特征
Eur J Gastroenterol Hepatol. 2000 Jul;12(7):745-9. doi: 10.1097/00042737-200012070-00005.
3
Heterotopic gastric mucosa of the esophagus: literature-review and proposal of a clinicopathologic classification.食管异位胃黏膜：文献综述及临床病理分类建议
Am J Gastroenterol. 2004 Mar;99(3):543-51. doi: 10.1111/j.1572-0241.2004.04082.x.
4
Heterotopic gastric mucosa (inlet patch): endoscopic prevalence, histopathological, demographical and clinical characteristics.异位性胃黏膜（入口斑）：内镜检出率、组织病理学、人口统计学和临床特征。
Int J Clin Pract. 2009 Feb;63(2):287-91. doi: 10.1111/j.1742-1241.2006.01215.x. Epub 2007 May 29.
5
Heterotopic gastric mucosa (inlet patch) in a patient with laryngopharyngeal reflux (LPR) and laryngeal carcinoma: a case report and review of literature.喉咽反流（LPR）和喉癌患者的异位胃黏膜（入口斑）：一例病例报告及文献复习
Dis Esophagus. 2009;22(4):E1-5. doi: 10.1111/j.1442-2050.2008.00915.x.
6
The rare presentations of a large polyp and an esophageal carcinoma in heterotropic gastric mucosa: a case series.胃黏膜异位症中巨大息肉与食管癌的罕见表现：病例系列报道
J Med Case Rep. 2007 Nov 2;1:127. doi: 10.1186/1752-1947-1-127.
7
Heterotopic gastric mucosa of upper oesophagus: evaluation of 12 cases during gastroscopic examination.食管上段异位胃黏膜：12例胃镜检查评估
Prz Gastroenterol. 2014;9(5):302-6. doi: 10.5114/pg.2014.45490. Epub 2014 Oct 19.
8
Study of Helicobacter pylori colonization of patches of heterotopic gastric mucosa (HGM) at the upper esophagus.食管上段异位胃黏膜（HGM）斑块中幽门螺杆菌定植的研究。
Dig Dis Sci. 1993 Jan;38(1):142-6. doi: 10.1007/BF01296787.
9
A 14-Year Study of 398 Esophageal Adenocarcinomas Diagnosed Among 156,256 EGDs Performed at Two Large Hospitals: An Inlet Patch Is Proposed as a Significant Risk Factor for Proximal Esophageal Adenocarcinoma.在两家大医院进行的 156256 次内镜检查中诊断出 398 例食管腺癌：14 年研究结果表明，入口补丁被认为是近端食管腺癌的一个重要危险因素。
Dig Dis Sci. 2018 Feb;63(2):452-465. doi: 10.1007/s10620-017-4878-2. Epub 2017 Dec 16.
10
Esophageal inlet patch.食管入口斑
Radiol Res Pract. 2011;2011:460890. doi: 10.1155/2011/460890. Epub 2011 Mar 30.
引用本文的文献
1
A systematic review of fully circumferential inlet patches (heterotopic gastric mucosa): More complicated than regular inlet patches.全周性入口黏膜片（异位胃黏膜）的系统评价：比普通入口黏膜片更复杂。
Indian J Gastroenterol. 2025 Mar 31. doi: 10.1007/s12664-025-01738-y.
2
A Rare Cause of Food Impaction: Heterotopic Gastric Mucosa.食物嵌塞的罕见原因：异位胃黏膜。
GE Port J Gastroenterol. 2021 Nov 4;29(6):439-441. doi: 10.1159/000519928. eCollection 2022 Nov.
3
Heterotopic Gastric Mucosa in the Proximal Esophagus: Prospective Study and Systematic Review on Relationships with Endoscopic Findings and Clinical Data.近端食管异位胃黏膜：关于其与内镜检查结果及临床数据关系的前瞻性研究与系统评价
Dysphagia. 2023 Apr;38(2):629-640. doi: 10.1007/s00455-022-10492-8. Epub 2022 Jul 9.
4
Issues and controversies in esophageal inlet patch.食管入口补片的问题与争议
World J Gastroenterol. 2019 Aug 14;25(30):4061-4073. doi: 10.3748/wjg.v25.i30.4061.
本文引用的文献
1
Argon plasma coagulation of cervical heterotopic gastric mucosa as an alternative treatment for globus sensations.氩等离子体凝固术治疗宫颈异位胃黏膜引起的咽部异物感的替代疗法
Gastroenterology. 2009 Aug;137(2):440-4. doi: 10.1053/j.gastro.2009.04.053. Epub 2009 May 4.
2
Inlet patch: associations with endoscopic findings in the upper gastrointestinal system.入口黏膜斑：与上消化道系统内镜检查结果的关联
Scand J Gastroenterol. 2008 Aug;43(8):910-4. doi: 10.1080/00365520801986619.
3
Argon plasma ablation of gastric inlet patches in the cervical esophagus may alleviate globus sensation: a pilot trial.氩等离子体消融治疗颈段食管胃入口斑块可能缓解咽部异物感：一项试点试验。
Endoscopy. 2006 Jun;38(6):566-70. doi: 10.1055/s-2006-925362.
4
Heterotopic gastric mucosa in the cervical esophagus (inlet patch): endoscopic prevalence, histological and clinical characteristics.宫颈段食管的异位胃黏膜（入口斑）：内镜下患病率、组织学及临床特征
J Gastroenterol Hepatol. 2004 Aug;19(8):891-6. doi: 10.1111/j.1440-1746.2004.03474.x.
5
Heterotopic gastric mucosa of the esophagus: literature-review and proposal of a clinicopathologic classification.食管异位胃黏膜：文献综述及临床病理分类建议
Am J Gastroenterol. 2004 Mar;99(3):543-51. doi: 10.1111/j.1572-0241.2004.04082.x.
6
Inlet patch: prevalence, histologic type, and association with esophagitis, Barrett esophagus, and antritis.入口黏膜片：患病率、组织学类型及其与食管炎、巴雷特食管和胃窦炎的关联。
Arch Pathol Lab Med. 2004 Apr;128(4):444-7. doi: 10.5858/2004-128-444-IPPHTA.
7
Dysphagia due to a diaphragm-like localized narrowing in the lower esophagus (lower esophageal ring).因食管下段类似膈膜的局限性狭窄（食管下环）导致的吞咽困难。
Am J Roentgenol Radium Ther Nucl Med. 1953 Dec;70(6):911-22.
8
Gastric heterotopia in the proximal esophagus complicated by stricture.近端食管胃异位伴狭窄
Gastrointest Endosc. 2003 Jan;57(1):131-3. doi: 10.1067/mge.2003.44.
9
Adenocarcinoma of the upper esophagus arising in heterotopic gastric mucosa: common pathogenesis with Barrett's adenocarcinoma?异位胃黏膜中发生的食管上段腺癌：与巴雷特腺癌有共同的发病机制吗？
Virchows Arch. 2002 Oct;441(4):406-11. doi: 10.1007/s00428-002-0697-7.
10
Heterotopic gastric mucosa in the upper esophagus: a prospective study of 33 cases and review of literature.食管上段异位胃黏膜：33例前瞻性研究及文献复习
Endoscopy. 1997 Oct;29(8):710-5. doi: 10.1055/s-2007-1004294.
Zotero 插件