当你开具质子泵抑制剂时需要了解的事项。
What you need to know when you prescribe a proton pump inhibitor.
作者信息
Norman A, Hawkey C J
机构信息
Nottingham Digestive Diseases Centre, University Hospitals Trust, Nottingham, UK.
出版信息
Frontline Gastroenterol. 2011 Oct;2(4):199-205. doi: 10.1136/flgastro-2011-100006. Epub 2011 Jun 24.
Abstract
Ever since they were launched, proton pump inhibitors (PPIs) have been regarded as profligate prescription interventions and have become a favourite target for pharmacy advisers. Now that they are cheap, with generic omeprazole 20 mg daily costing £1.88 per month (£24.51 per annum) in the UK, it is time to ask whether this status should be reviewed, whether there are areas where the message should be reversed and whether there are any circumstances in which the extra cost of branded PPIs or combined preparations is justified. Equally, with the recognition of an extended toxicity profile, is prescribing profligacy not an economic but a safety issue?
摘要
自从质子泵抑制剂（PPIs）问世以来，它们一直被视为过度使用的处方干预措施，并且已成为药房顾问们青睐的目标。如今它们价格低廉，在英国，每日服用20毫克的非专利奥美拉唑每月花费1.88英镑（每年24.51英镑），现在是时候问问这种状况是否应该重新审视，是否存在应该扭转这种观念的领域，以及是否存在任何情况下品牌质子泵抑制剂或复方制剂的额外成本是合理的。同样，随着对其毒性范围扩大的认识，过度开药难道不是一个安全问题而非经济问题吗？
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