Suppr超能文献

在重新制定围手术期管理方案后,加快食管鳞状细胞癌食管切除及重建术后的恢复。

Expedite recovery from esophagectomy and reconstruction for esophageal squamous cell carcinoma after perioperative management protocol reinvention.

作者信息

Liu Yu-Wei, Yan Fan-Wei, Tsai Dong-Lin, Li Hsien-Pin, Lee Yen-Lung, Chiang Hung-Hsing, Hsu Hung-Te, Chuang Hung-Yi, Chou Shah-Hwa

机构信息

Department of Surgery, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.

Department of Anesthesia, Kaohsiung Municipal Ta-Tung Hospital, Kaohsiung, Taiwan.

出版信息

J Thorac Dis. 2017 Jul;9(7):2029-2037. doi: 10.21037/jtd.2017.06.13.

Abstract

BACKGROUND

Surgery for esophageal cancer is invasive and challenging, and always to be followed with arduous post-operative care and recovery. This study, maybe one of the first in Asian populations, is to determine whether a reinvented protocol for perioperative management for esophageal cancer surgery which is being implemented in our department, will lead to a faster convalescence and also significantly decrease financial burdens garnered by patients during hospitalization.

METHODS

Operated on by the same surgeon and team in the same hospital, consecutive patients who had received esophagectomy and reconstruction for esophageal squamous cell carcinoma were retrospectively reviewed. On the basis of two different treatment periods, patients were divided into two groups: A and B. Group A was patients who had received the new reinvented protocol between 2012 and 2016, while group B patients were those having received the previous protocol between 2008 and 2011. Their demographics, post-operative outcome, and hospital charges were collected and compared.

RESULTS

There were 64 patients in group A, and 69 in group B. Ventilator days (P<0.001), ICU stay (P<0.001), and post-operative stay (P<0.001) were significantly shorter in group A patients. Complication rates were similar between the two groups. No hospital mortality was noted in either group. Hospital charges in group A were found to be perceptively lower, although not statistically significant (P value =0.078).

CONCLUSIONS

The current protocol of perioperative care effectively ameliorated convalescence after esophagectomy and reconstruction for esophageal squamous cell carcinoma without increasing complication rate or mortality. It is also potentially more practical in future health care policies during this era of financial shortage.

摘要

背景

食管癌手术具有侵入性且颇具挑战性,术后还需进行艰苦的护理和康复。本研究可能是亚洲人群中的首批研究之一,旨在确定我院正在实施的一种重新设计的食管癌手术围手术期管理方案是否能使患者康复更快,并显著减轻患者住院期间的经济负担。

方法

回顾性分析在同一家医院由同一外科医生和团队进行手术的连续食管癌鳞状细胞癌患者,这些患者均接受了食管切除术和重建术。根据两个不同的治疗时期,将患者分为两组:A组和B组。A组为2012年至2016年期间接受新重新设计方案的患者,B组为2008年至2011年期间接受先前方案的患者。收集并比较两组患者的人口统计学数据、术后结果和住院费用。

结果

A组有64例患者,B组有69例患者。A组患者的呼吸机使用天数(P<0.001)、重症监护病房停留时间(P<0.001)和术后住院时间(P<0.001)明显更短。两组的并发症发生率相似。两组均未观察到医院死亡病例。A组的住院费用明显较低,尽管无统计学意义(P值=0.078)。

结论

目前的围手术期护理方案有效改善了食管癌鳞状细胞癌食管切除术后的康复情况,且未增加并发症发生率或死亡率。在这个资金短缺的时代,该方案在未来的医疗保健政策中可能也更具实用性。

相似文献

2
An audit of surgical outcomes of esophageal squamous cell carcinoma.
Eur J Cardiothorac Surg. 2007 Mar;31(3):536-44. doi: 10.1016/j.ejcts.2006.12.002. Epub 2007 Jan 11.
3
Cost-Effectiveness of Minimally Invasive Esophagectomy for Esophageal Squamous Cell Carcinoma.
World J Surg. 2018 Aug;42(8):2522-2529. doi: 10.1007/s00268-018-4501-5.
6
Outcomes of Endoscopic Submucosal Dissection vs Esophagectomy for T1 Esophageal Squamous Cell Carcinoma in a Real-World Cohort.
Clin Gastroenterol Hepatol. 2019 Jan;17(1):73-81.e3. doi: 10.1016/j.cgh.2018.04.038. Epub 2018 Apr 25.
7
Outcomes, quality of life, and survival after esophagectomy for squamous cell carcinoma: A propensity score-matched comparison of operative approaches.
J Thorac Cardiovasc Surg. 2015 Apr;149(4):1006-14; discussion 1014- 5.e4. doi: 10.1016/j.jtcvs.2014.12.063. Epub 2015 Jan 9.
9
Efficacy of perioperative immunonutrition in esophageal cancer patients undergoing esophagectomy.
Nutrition. 2019 Mar;59:96-102. doi: 10.1016/j.nut.2018.08.006. Epub 2018 Aug 22.

引用本文的文献

1
The evolution of fast track protocols after oesophagectomy.
J Thorac Dis. 2019 Apr;11(Suppl 5):S675-S684. doi: 10.21037/jtd.2018.11.63.
2
Change in tongue pressure and the related factors after esophagectomy: a short-term, longitudinal study.
Esophagus. 2019 Jul;16(3):300-308. doi: 10.1007/s10388-019-00668-x. Epub 2019 Apr 2.

本文引用的文献

1
Immediate Postoperative Oral Nutrition Following Esophagectomy: A Multicenter Clinical Trial.
Ann Thorac Surg. 2016 Oct;102(4):1141-8. doi: 10.1016/j.athoracsur.2016.04.067. Epub 2016 Jun 17.
2
Combined thoracoscopic-laparoscopic esophagectomy versus open esophagectomy: a meta-analysis of outcomes.
Surg Endosc. 2016 Sep;30(9):3873-81. doi: 10.1007/s00464-015-4692-x. Epub 2015 Dec 10.
3
Is hand sewing comparable with stapling for anastomotic leakage after esophagectomy? A meta-analysis.
World J Gastroenterol. 2014 Dec 7;20(45):17218-26. doi: 10.3748/wjg.v20.i45.17218.
4
Inter-device differences in monitoring for goal-directed fluid therapy.
Can J Anaesth. 2015 Feb;62(2):169-81. doi: 10.1007/s12630-014-0265-z. Epub 2014 Nov 13.
5
6
The effect of formalizing enhanced recovery after esophagectomy with a protocol.
Dis Esophagus. 2015 Aug-Sep;28(6):567-73. doi: 10.1111/dote.12234. Epub 2014 May 18.
8
Initial experiences of an enhanced recovery protocol in esophageal surgery.
World J Surg. 2013 Oct;37(10):2372-8. doi: 10.1007/s00268-013-2135-1.
9
Review of open and minimal access approaches to oesophagectomy for cancer.
Br J Surg. 2010 Dec;97(12):1845-53. doi: 10.1002/bjs.7231. Epub 2010 Oct 4.
10
Radical resection or chemoradiotherapy for cervical esophageal cancer?
World J Surg. 2010 Aug;34(8):1832-9. doi: 10.1007/s00268-010-0595-0.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验