Zeller Michelle P, Barty Rebecca, Aandahl Astrid, Apelseth Torunn O, Callum Jeannie, Dunbar Nancy M, Elahie Allahna, Garritsen Henk, Hancock Helen, Kutner José Mauro, Manukian Belinda, Mizuta Shuichi, Okuda Makoto, Pagano Monica B, Pogłód Ryszard, Rushford Kylie, Selleng Kathleen, Sørensen Claess Henning, Sprogøe Ulrik, Staves Julie, Weiland Thorsten, Wendel Silvano, Wood Erica M, van de Watering Leo, van Wordragen-Vlaswinkel Maria, Ziman Alyssa, Jan Zwaginga Jaap, Murphy Michael F, Heddle Nancy M, Yazer Mark H
McMaster Centre for Transfusion Research, McMaster University, Hamilton, Ontario, Canada.
Canadian Blood Services, Ancaster, Ontario, Canada.
Transfusion. 2017 Oct;57(10):2329-2337. doi: 10.1111/trf.14255. Epub 2017 Aug 25.
Transfusion of group O blood to non-O recipients, or transfusion of D- blood to D+ recipients, can result in shortages of group O or D- blood, respectively. This study investigated RBC utilization patterns at hospitals around the world and explored the context and policies that guide ABO blood group and D type selection practices.
This was a retrospective study on transfusion data from the 2013 calendar year. This study included a survey component that asked about hospital RBC selection and transfusion practices and a data collection component where participants submitted information on RBC unit disposition including blood group and D type of unit and recipient. Units administered to recipients of unknown ABO or D group were excluded.
Thirty-eight hospitals in 11 countries responded to the survey, 30 of which provided specific RBC unit disposition data. Overall, 11.1% (21,235/191,397) of group O units were transfused to non-O recipients; 22.6% (8777/38,911) of group O D- RBC units were transfused to O D+ recipients, and 43.2% (16,800/38,911) of group O D- RBC units were transfused to recipients that were not group O D-. Disposition of units and hospital transfusion policy varied within and across hospitals of different sizes, with transfusion of group O D- units to non-group O D- patients ranging from 0% to 33%.
A significant proportion of group O and D- RBC units were transfused to compatible, nonidentical recipients, although the frequency of this practice varied across sites.
将O型血输给非O型受血者，或将D阴性血输给D阳性受血者，可能分别导致O型血或D阴性血短缺。本研究调查了世界各地医院红细胞的使用模式，并探讨了指导ABO血型和D血型选择实践的背景和政策。
这是一项对2013年日历年输血数据的回顾性研究。本研究包括一个调查部分，询问医院红细胞的选择和输血实践，以及一个数据收集部分，参与者提交有关红细胞单位处置的信息，包括单位和受血者的血型和D型。输给ABO或D组不明的受血者的单位被排除。
11个国家的38家医院对调查做出了回应，其中30家提供了具体的红细胞单位处置数据。总体而言，11.1%（21,235/191,397）的O型单位被输给非O型受血者；22.6%（8777/38,911）的O型D阴性红细胞单位被输给O型D阳性受血者，43.2%（16,800/38,911）的O型D阴性红细胞单位被输给非O型D阴性的受血者。不同规模医院内部和之间的单位处置和医院输血政策各不相同，将O型D阴性单位输给非O型D阴性患者的比例从0%到33%不等。
相当一部分O型和D阴性红细胞单位被输给了相容但不同型的受血者，尽管这种做法的频率在不同地点有所不同。
