Lee So-Yeon, Shin Yu Ri, Park Hee Jin, Rho Myung Ho, Chung Eun Chul
Department of Radiology, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Jongno-gu, Seoul, Republic of Korea.
Department of Radiology, College of Medicine, Incheon St. Mary's Hospital, The Catholic University of Korea, Bupyeong-gu, Incheon, Republic of Korea.
PLoS One. 2017 Aug 25;12(8):e0183744. doi: 10.1371/journal.pone.0183744. eCollection 2017.
The diagnosis of ossification of the posterior longitudinal ligament (OPLL) on magnetic resonance imaging (MRI) is challenging. The purpose of this study is to evaluate the usefulness of the multiecho fast field echo (mFFE) MRI in the detection of ossification of the posterior longitudinal ligament and dural ossification (DO) of the cervical spine.
Sixty-three patients who underwent MRI with mFFE and CT for cervical spine were retrospectively evaluated. The presence of OPLL and DO on MR images was assessed by two independent readers. The sensitivity, specificity, and accuracy of MRI for detecting OPLL and DO were determined using CT as a reference standard. Image contrast ratios were obtained between the OPLL and perilesional structures on each sequence.
There were 31 patients with OPLL and 13 DO lesions. The mean sensitivity, specificity, and accuracy of both readers were 94%, 81%, 88% for OPLL and 92%, 81%, 86% for DO, respectively. The contrast ratios for OPLL and intervertebral disc, spinal cord and cerebrospinal fluid were significantly superior on mFFE images, whereas those for OPLL and bone marrow were significantly inferior on mFFE images than those of T1-and T2-weighted images (p ≤ 0.016).
MRI with mFFE may be sufficient for the assessment of OPLL and DO, with good contrasts between OPLL and intervertebral disc, spinal cord, and cerebrospinal fluid.
在磁共振成像（MRI）上诊断后纵韧带骨化（OPLL）具有挑战性。本研究的目的是评估多回波快速场回波（mFFE）MRI在检测颈椎后纵韧带骨化和硬脊膜骨化（DO）方面的实用性。
回顾性评估63例接受颈椎mFFE MRI和CT检查的患者。由两名独立阅片者评估MR图像上OPLL和DO的存在情况。以CT作为参考标准，确定MRI检测OPLL和DO的敏感性、特异性和准确性。在每个序列上获取OPLL与病变周围结构之间的图像对比率。
有31例患者存在OPLL，13例存在DO病变。两位阅片者对OPLL的平均敏感性、特异性和准确性分别为94%、81%、88%，对DO的分别为92%、81%、86%。在mFFE图像上，OPLL与椎间盘、脊髓和脑脊液的对比率显著更高，而在mFFE图像上OPLL与骨髓的对比率显著低于T1加权和T2加权图像（p≤0.016）。
mFFE MRI可能足以评估OPLL和DO，OPLL与椎间盘、脊髓和脑脊液之间具有良好的对比度。
