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The Proteomic Landscape of Human Ex Vivo Regulatory and Conventional T Cells Reveals Specific Metabolic Requirements.人类体外调节性T细胞和传统T细胞的蛋白质组学图谱揭示了特定的代谢需求。
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Sphingosine-1-Phosphate Signalling Inhibition Suppresses Th1-Like Treg Generation by Reversing Mitochondrial Uncoupling.鞘氨醇-1-磷酸信号抑制通过逆转线粒体解偶联来抑制Th1样调节性T细胞的产生。
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Metabolic regulation of forkhead box P3 alternative splicing isoforms and their impact on health and disease.叉头框蛋白 P3 选择性剪接异构体的代谢调控及其对健康和疾病的影响。
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Front Immunol. 2022 Dec 2;13:1005965. doi: 10.3389/fimmu.2022.1005965. eCollection 2022.
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Glucose promotes regulatory T cell differentiation to maintain intestinal homeostasis.葡萄糖促进调节性T细胞分化以维持肠道稳态。
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TNFR2 Costimulation Differentially Impacts Regulatory and Conventional CD4 T-Cell Metabolism.TNFR2 共刺激作用对调节性和常规 CD4 T 细胞代谢的影响不同。
Front Immunol. 2022 Jun 30;13:881166. doi: 10.3389/fimmu.2022.881166. eCollection 2022.
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Fatty Acid Metabolism and T Cells in Multiple Sclerosis.脂肪酸代谢与多发性硬化症中的 T 细胞。
Front Immunol. 2022 May 4;13:869197. doi: 10.3389/fimmu.2022.869197. eCollection 2022.
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Gene Doping with Peroxisome-Proliferator-Activated Receptor Beta/Delta Agonists Alters Immunity but Exercise Training Mitigates the Detection of Effects in Blood Samples.过氧化物酶体增殖物激活受体β/δ激动剂基因兴奋剂会改变免疫功能,但运动训练可减轻血液样本中效应的检测。
Int J Mol Sci. 2021 Oct 25;22(21):11497. doi: 10.3390/ijms222111497.
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6-Phosphogluconate dehydrogenase (6PGD), a key checkpoint in reprogramming of regulatory T cells metabolism and function.6-磷酸葡萄糖酸脱氢酶(6PGD)是调节性 T 细胞代谢和功能重编程的关键检查点。
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Tissue Nutrient Environments and Their Effect on Regulatory T Cell Biology.组织营养环境及其对调节性 T 细胞生物学的影响。
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Metabolic Choice Tunes Foxp3+ Regulatory T Cell Function.代谢选择调节Foxp3+调节性T细胞功能。
Adv Exp Med Biol. 2021;1278:81-94. doi: 10.1007/978-981-15-6407-9_5.

The Proteomic Landscape of Human Ex Vivo Regulatory and Conventional T Cells Reveals Specific Metabolic Requirements.

作者信息

Procaccini Claudio, Carbone Fortunata, Di Silvestre Dario, Brambilla Francesca, De Rosa Veronica, Galgani Mario, Faicchia Deriggio, Marone Gianni, Tramontano Donatella, Corona Marco, Alviggi Carlo, Porcellini Antonio, La Cava Antonio, Mauri Pierluigi, Matarese Giuseppe

出版信息

Immunity. 2016 Mar 15;44(3):712. doi: 10.1016/j.immuni.2016.02.022.

DOI:10.1016/j.immuni.2016.02.022
PMID:28843073
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5641922/
Abstract
摘要