Mitchelmore Philip J, Randall Joanna, Bull Matthew J, Moore Karen A, O'Neill Paul A, Paszkiewicz Konrad, Mahenthiralingam Eshwar, Scotton Chris J, Sheldon Christopher D, Withers Nicholas J, Brown Alan R
Institute of Biomedical and Clinical Sciences, University of Exeter Medical School, Exeter, UK.
Department of Respiratory Medicine, Royal Devon and Exeter NHS Foundation Trust, Exeter, UK.
Thorax. 2017 Aug 26. doi: 10.1136/thoraxjnl-2016-209889.
While (PA) cross-infection is well documented among patients with cystic fibrosis (CF), the equivalent risk among patients with non-CF bronchiectasis (NCFB) is unclear, particularly those managed alongside patients with CF. We performed analysis of PA within a single centre that manages an unsegregated NCFB cohort alongside a segregated CF cohort. We found no evidence of cross-infection between the two cohorts or within the segregated CF cohort. However, within the unsegregated NCFB cohort, evidence of cross-infection was found between three (of 46) patients. While we do not presently advocate any change in the management of our NCFB cohort, longitudinal surveillance is clearly warranted.
