Faculty of Social Sciences, Radboud University, Nijmegen, The Netherlands.
Department of Human Genetics, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, The Netherlands.
Psychiatry Res. 2017 Dec;258:255-261. doi: 10.1016/j.psychres.2017.08.037. Epub 2017 Aug 19.
Deficits in multiple neuropsychological domains and specific personality profiles have been observed in attention-deficit/hyperactivity disorder (ADHD). In this study we investigated whether personality traits are related to neurocognitive profiles in adults with ADHD. Neuropsychological performance and Five Factor Model (FFM) personality traits were measured in adults with ADHD (n = 133) and healthy controls (n = 132). Three neuropsychological profiles, derived from previous community detection analyses, were investigated for personality trait differences. Irrespective of cognitive profile, participants with ADHD showed significantly higher Neuroticism and lower Extraversion, Agreeableness, and Conscientiousness than healthy controls. Only the FFM personality factor Openness differed significantly between the three profiles. Higher Openness was more common in those with aberrant attention and inhibition than those with increased delay discounting and atypical working memory / verbal fluency. The results suggest that the personality trait Openness, but not any other FFM factor, is linked to neurocognitive profiles in ADHD. ADHD symptoms rather than profiles of cognitive impairment have associations with personality traits.
在注意缺陷多动障碍(ADHD)患者中,多个神经心理学领域和特定的人格特征存在缺陷。在这项研究中,我们研究了人格特征是否与 ADHD 成年患者的神经认知特征有关。我们对 ADHD 成年患者(n=133)和健康对照组(n=132)进行了神经心理学表现和五因素模型(FFM)人格特征的测量。研究了三个源自先前社区检测分析的神经认知特征,以探究人格特征差异。无论认知特征如何,ADHD 患者的神经质水平明显高于健康对照组,而外向性、宜人性和尽责性则明显低于健康对照组。只有 FFM 人格因素开放性在这三个特征之间有显著差异。注意力和抑制异常的患者中,开放性较高的比例明显高于延迟折扣和非典型工作记忆/言语流畅性增加的患者。结果表明,人格特质开放性,而不是任何其他 FFM 因素,与 ADHD 中的神经认知特征有关。ADHD 症状而不是认知障碍的特征与人格特质有关。